Project Grant W81XWH1710598

This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) will provide $790,101.20 to The Research Foundation For The State University Of New York to study the benefits of nicotinamide riboside supplementation on sleep quality, sleep duration, and cognitive function in older adults. The 1-year project builds upon prior VA-funded research and will assess sleep metrics, cognitive performance, and serum brain-derived neurotrophic factor levels in older...

This Project Grant award of $154,280 from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) will support research to identify biomolecular targets within plasma extracellular vesicles that may mediate the cognitive benefits of aerobic exercise in older adults with remitted late-life depression (RLLD). The study will leverage data from an ongoing K23 clinical trial on the effects of 6 months of aerobic exercise training versus social...

This Project Grant award from the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420) provides $2,031,972.00 to Deakin University in Australia to conduct a randomized, placebo-controlled, double-blind clinical trial on the use of SILEXAN to treat post-traumatic stress disorder (PTSD). The trial will run from September 1, 2023 to August 31, 2027. As an established research institution, Deakin University has previously conducted federally funded work...

The U.S. Defense Health Agency awarded a $817,027 Project Grant to The Roskamp Institute, Inc. in Sarasota, Florida under the Military Medical Research and Development program (CFDA 12.420). The 3-year grant, running from August 15, 2023 to August 14, 2026, will support the institute's research on an "amnion-derived multipotent cell secretome-medicated therapy for Gulf War Illness." The Roskamp Institute is a non-profit biotechnology research organization that has previously...

This $1,224,089 Department of Defense Project Grant awarded on September 30, 2023 to Texas A&M University System Health Science Center will fund a 3-year research project titled "CONTRIBUTION OF CELLULAR SENESCENCE AND BRAIN AGING TO COGNITIVE DYSFUNCTION IN GWI". The project will be conducted under the Department of Defense's Military Medical Research and Development program (CFDA 12.420), which supports a broad range of biomedical research to transform healthcare for Service...

This federal Project Grant award from the National Institute of Mental Health (CFDA 93.242 Mental Health Research Grants) provides $976,424 to The General Hospital Corporation, doing business as Massachusetts General Hospital (MGH), to conduct a randomized controlled trial of a preventive behavioral intervention called Resilience Training (RT) for young adults with psychotic experiences. The study aims to evaluate whether RT can reduce psychotic experiences, anxiety, depression, and...

This Project Grant award, funded by the Department of the Army Medical Command under the Military Medical Research and Development program (CFDA 12.420), provides $1,704,652.00 to Trustees of Boston University (Boston University Medical Campus) to conduct research on the translational impact of genetic susceptibility to complex toxic exposures on blood-brain barrier function and age-related neurological outcomes in Gulf War Illness (GWI). The award period runs from September 1, 2024 to August...

This Project Grant award from the Department of the Army Medical Command under the Military Medical Research and Development program (CFDA 12.420) provides $713,277 to Boston University Medical Campus to conduct research on the translational impact of genetic susceptibility to complex toxic exposures on blood-brain barrier function and age-related neurological outcomes in Gulf War Illness. The award will support the project from September 1, 2024 through August 31, 2027. As part of this...

The Defense Health Agency awarded a $749,905 Project Grant to The Roskamp Institute Inc. under the Military Medical Research and Development federal grant program (CFDA 12.420). The grant will fund research from September 2023 through September 2026 to investigate microglial NOX2/NLRP3 inflammasome activation and its role in driving tau pathology and cognitive impairments in chronic traumatic brain injury. Specifically, the Roskamp Institute will conduct basic, applied, and advanced biomedical...

The U.S. Defense Health Agency awarded a $817,200 Project Grant under the Military Medical Research and Development program (CFDA 12.420) to The Roskamp Institute, Inc. in Sarasota, Florida. The grant, awarded on September 1, 2024, will support a 3-year research project titled "Targeting APOE Bioenergetics for Reducing the Risk of Neurodegeneration After Chronic Traumatic Brain Injury." The research aims to investigate mitochondrial bioenergetics, tau protein pathology,...