Project Grant W81XWH1510643

This Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB), under the federal Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), provides $124,562 to the University of Southern California to develop a highly multiplexed Raman imaging platform for studying the immune system's role in Alzheimer's disease. The award will fund the creation of a nanoparticle-based approach capable of simultaneously...

The National Science Foundation (NSF) Division of Chemical, Bioengineering, Environmental, and Transport Systems awarded a $300,000 EAGER (Early-Concept Grants for Exploratory Research) project grant to The Research Foundation for The State University of New York (RF SUNY) to establish near-ultraviolet (NUV) coherent anti-Stokes Raman scattering (CARS) microscopy for highly sensitive imaging of native biomolecules. This technology will be applied to develop label-free digital pathology for brain...

The University of Illinois has been awarded a $1,870,822 Project Grant from the National Institute on Aging's Aging Research program (CFDA 93.866) to develop new super-resolution fluorescence microscopy techniques. The goal is to achieve ultra-high resolution imaging of native amyloid-alpha receptors (AMPARs) in brain slices to study synaptic plasticity in both healthy and tauopathy conditions. The research will utilize multi-color imaging and digital image reconstruction methods to isolate...

The National Institutes of Health (NIH) awarded a $1,843,229 Cooperative Agreement under the Trans-NIH Research Support program (CFDA 93.310) to Stanford University, with a project period from September 15, 2025 to August 31, 2027. The project aims to develop a combined Shortwave Infrared (SWIR) Fluorescence and Raman imaging system to enable real-time, high-resolution visualization of tissue structures below the surface. Key objectives include optimizing SWIR Raman imaging to characterize...

This federal Project Grant award of $2,217,454.00, awarded by the Department of the Army Medical Command under the Military Medical Research and Development program (CFDA 12.420), supports a research study on the effects of transcranial photobiomodulation (PBM) in older adults with traumatic brain injury. The primary awardee is the Research Foundation of the City University of New York, which is collaborating with New York University School of Medicine as a sub-grantee. The research aims to...

This Project Grant award for $901,906 from the Defense Health Agency supports research to develop "AUTOMATIC RAPID, HIGH RESOLUTION METABOLIC IMAGING FOR IMPROVED MANAGEMENT OF PATIENTS WITH GLIOMA". The funding is provided through the Military Medical Research and Development program (CFDA 12.420) which focuses on biomedical research to address military and veteran health needs. The research, conducted by the Regents of the University of California, San Francisco (UCSF), aims to...

This federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Drug Use and Addiction Research Programs (CFDA 93.279), provides $1,702,003.00 to develop and assess the clinical potential of quantitative imaging biomarkers for evaluating changes in myofiber microstructure associated with masticatory myofascial pain syndrome (MMPS). The key products and services to be delivered include: 1) Establishing an optimal 15-minute MRI protocol and...

This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) to Tauvision, Inc. provides $493,384 to develop an eyedrop-based, non-invasive diagnostic test for Alzheimer's disease. The project aims to optimize a fluorescent compound that can label pathological protein aggregates in the eye and be imaged using standard ophthalmology equipment, allowing for a direct measurement of central nervous system biomarkers. In Phase 1, the researchers will improve the...

This $4.46 million project grant from the National Institute on Aging, part of the Department of Health and Human Services, supports research under the Aging Research program (CFDA 93.866) to develop a new in vivo magnetic resonance imaging biomarker for early detection of Alzheimer's disease neurodegeneration. Specifically, the awardee, Washington University, will utilize quantitative gradient recalled echo MRI techniques to identify two types of hippocampal tissue in preclinical and mild...

This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) provides $499,588 to develop non-radioactive nanoprobes for magnetic resonance imaging (MRI) of tropomyosin receptor kinase B (TrkB) in Alzheimer's disease. The goal is to create new MRI-based imaging tools to detect reduced TrkB expression, which is linked to impaired neurogenesis, synaptic damage, and neuronal death in Alzheimer's. The award recipient, Exqor Technologies Inc., will work to create a...