The New York Structural Biology Center, Inc. has been awarded a $1,995,724 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) to acquire a state-of-the-art 800 MHz NMR spectrometer console and associated probes. This instrumentation will enhance the capacity of the existing 800 MHz NMR system to support a range of NIH-funded structural biology research, from fundamental studies of biomolecular...
The National Institute of General Medical Sciences (NIGMS) awarded a $599,733 Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) to Florida State University (FSU). The grant supports the development of a new technology pathway towards 1.5 GHz 1H NMR spectroscopy by building a 28.2 T (1.2 GHz 1H)/1PPM, all-superconducting NMR demonstrator magnet. The project will utilize high-temperature superconductors (HTS) Bi-2212 and Bi-2223 nested inside an existing 12...
The National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training Program (CFDA 93.859), awarded a $1,469,739 Project Grant to the Research Foundation of the City University of New York (RFCUNY) to purchase a TIMSTOF-FLEX MALDI-2 high-resolution mass spectrometer. This advanced instrumentation will support biomedical research projects across 12 laboratories from CUNY and nearby institutions, focusing on areas such as conformational dynamics of...
The National Institute of General Medical Sciences (NIGMS) awarded a $1,048,299 Project Grant under the Biomedical Research and Research Training (CFDA 93.859) federal grant program to The Research Foundation for the State University of New York (RF-SUNY) on August 1, 2025. The funding will support the acquisition of a LUMICKS C-TRAP correlative force and fluorescence optical tweezer system, which will enable real-time observation, monitoring, and quantitation of interactions between...
This federal Project Grant award of $436,361 from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), supports the development of innovative tools and methods for probing the structure and dynamics of biological macromolecules using small and wide-angle X-ray scattering (SWAXS) analysis. The research program aims to significantly improve the resolution of density reconstruction from SWAXS data, develop new...
The National Institute of General Medical Sciences (NIGMS) awarded a $1,600,000 Project Grant under the Biomedical Research and Research Training (CFDA 93.859) program to Saint Louis University. The grant will fund the purchase of a high-sensitivity Bruker Q-band ELEXSYS E580 Pulse EPR Spectrometer to enable structural dynamics studies of proteins and their complexes, as well as the training of students and researchers. The instrument will support basic research projects from NIH-funded...
This Project Grant award from the National Institutes of Health (NIH) Office of Research Infrastructure Programs (CFDA 93.351) provides $750,000 to the University of Illinois to acquire a Bruker Avance NEO Nuclear Magnetic Resonance (NMR) spectrometer system. The NMR system, which operates at 500 MHz and includes an automated sample changer and cryogenically-cooled probe, will be used to support the research programs of the university's synthetic organic, inorganic, physical, and chemical...
The National Institute of General Medical Sciences (NIGMS) awarded a $3,999,999 Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) to the Icahn School of Medicine at Mount Sinai (ISMMS). The funding will support the purchase of a Glacios 2 cryo-electron microscope (cryo-EM) to enable ISMMS researchers to conduct advanced structural biology studies on diverse biological systems and disease mechanisms. The new cryo-EM instrument, equipped with a Falcon 4i...
This Project Grant award from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), provides $1,194,805.00 to Brightspec, Inc. to develop a Molecular Rotational Resonance (MRR) ratiometer. The MRR ratiometer is a spectroscopic instrument capable of precisely quantifying the relative abundances of components in complex mixtures, such as trace isotopologues, major and minor enantiomers, and various reaction...
The National Institute of General Medical Sciences (NIGMS) awarded a $528,000 Project Grant (CFDA 93.859 - Biomedical Research and Research Training) to the Sloan-Kettering Institute for Cancer Research located in New York, NY. The purpose of this 4-year grant, with a period of performance from September 30, 2024 to July 31, 2028, is to develop novel approaches to map the folding and protein occupancy of entire chromosomes with single-nucleosome resolution and single-molecule precision. The...