Using system dynamics modeling to foster real-time connections to care

Ended Project Grant Awarded Last action

Award ID
R61DA057675
Recipient
Awarding agency
Obligated
$3,068,938

Award facts

Assistance listing
93.310 Trans-NIH Research Support
Completion date
Originally
Place of performance
Connecticut, USA

Award details come from USAspending.gov.

Description

As the agency reported it.

Abstract
Since 1999, there has been a 400% increase in the rate of drug overdose (OD) deaths in the U.S., with over 70% of the deaths in 2019 related to opioids. The opioid crisis continues to worsen in the state of connecticut (CT) for all racial/ethnic, gender, and age groups, with the number of overdose deaths increasing by 285% from 2012 to 2020. While the deployment of first responders in the field for overdose, including police, fire, and emergency medical services, provides life-saving resuscitation and naloxone, IT is unknown whether other evidence-based interventions are available and being utilized. To date, we lack critical and actionable real-time data from first responders and emergency departments (EDS), including whether a treatment referral was offered to those who have overdosed, and from individuals who overdosed, such as time from overdose to treatment engagement. This real-time data could assist local authorities in predicting rates, timing, and location of overdoses, as well as the types of services needed. In response, our research team has partnered with the CT department of public health (DPH) to develop a system dynamics (SD) model that allows US to assess the impact of key interventions, including the implementation of good samaritan laws (gsls) and the widespread distribution of naloxone, on important clinical outcomes, such the number of OD deaths. This model has been carefully calibrated for CT and has already been used to identify where data gaps are limiting the development of evidence-based interventions (e.g., absence of information about bystander use of naloxone during OD event, etc.) and to predict the clinical outcomes that can anticipated if specific policy changes or interventions are pursued. Our team has also developed a comprehensive telehealth platform that can be deployed in the field where the overdose occurred or in the ED with minimal time or effort by existing staff. This platform will provide real-time access to providers who prescribe medication for opioid use disorder (moud) and other harm reduction services for high-risk individuals, and we hypothesize that IT will remove many of the barriers to follow up that these individuals face. Thus, the main objectives of this proposal are twofold: (1) to implement a novel, scalable, evidence-based, intervention (i.e., our telehealth platform) at the time of an opioid overdose that links people who have overdosed with access to medication for opioid use disorder (moud), harm reduction services, and recovery supports, and (2) to collect high-quality data about the processes and outcomes associated with deployment of this platform that can be integrated with our existing SD model to determine if, where, when, and what interventions should be implemented in the future. There is a great need to expedite and facilitate moud access and respond effectively to witnessed overdoses. Our long-term goal is to implement these novel SD modeling and telehealth strategies in CT, with subsequent dissemination nationally, ultimately improving access to moud and reducing OD events and fatalities.

Transactions

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Subawards

Subrecipient Amount Awarded
Center For Progressive Recovery LLC "In order to accomplish the above, CPR will engage in the following non-exhaustive list of activities: • Review of Yale’s Research Plan • Assist in the securing… $71,442
Long Island University Dr. Pantalon is the Corresponding PI for this subaward from Dr. Heckmann’s NIDA-funded Yale randomized controlled trial (RCT) of opioid use disorder treatment… $60,926
Center For Progressive Recovery LLC Center for Progressive Recovery, LLC will provide the following as deliverables and evidence of its successful completion of the tasks described in this… $147,353
Research Foundation Of The City University Of New York DR. Nasim s. Sabounchi, will be the subcontractor principal investigator. She will be the lead person for technological aspects of the project s system dynamics… $146,345
Research Foundation Of The City University Of New York Dr. Nasim S. Sabounchi, will be the subcontractor principal investigator. She will be the lead person for technological aspects of the project’s system… $349,233
Center For Progressive Recovery LLC In order to accomplish the above, CPR will engage in the following non-exhaustive list of activities: • Review of Yale’s Research Plan • Assist in the… $76,275

Quick answers

Who received award R61DA057675?

R61DA057675 was awarded to Yale Univ by National Institute on Drug Abuse (National Institutes of Health) on September 30, 2022.

How much is award R61DA057675 worth?

$3,068,938 has been obligated on R61DA057675.

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