Project Grant R44NS129492
- This Small Business Innovation Research (SBIR) Phase I project, awarded by the National Science Foundation (NSF) under the TIP (Technology, Innovation, and Partnerships) program (CFDA 47.084), aims to develop a novel, multifunctional neural probe for advancing neuroscience research. The $254,456 grant awarded to Neurobionics Inc. on August 15, 2024, will fund the integration of electrical, optical, and chemical capabilities into a single implantable device. This versatile tool will enable...
- Federal Project Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded The Johns Hopkins University a $616,585 Project Grant effective May 1, 2026 through April 30, 2031, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). This award funds the development of tools and methodologies to enable brain-wide chronic electrophysiology recording in freely moving rodents using next-generation Neuropixels...
- This federal Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), provides $2,415,243 to The Broad Institute, Inc. to develop a scalable, cloud-based framework for multi-modal mapping across single neuron omics, morphology, and electrophysiology. The framework aims to enable integrative, data-driven characterization of brain cell types, leveraging federated Brain Initiative resources and community engagement....
- This $2,623,223 Project Grant awarded by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) will fund the development of CLOUDSLEAP, a cloud-based platform to enhance accessibility to deep learning-based motion capture technology for behavior quantification. The key products and services to be delivered through this 3-year grant include: Enabling annotation, visualization, and sharing of pose tracking datasets directly from the browser,...
- Federal Project Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded $262,089 to Lawrence Berkeley National Laboratory on September 15, 2025, under the 21st Century Cures Act - Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative (CFDA 93.372) to enhance the AQNWB (Advancing Quantitative Neurophysiology with NWB) platform. AQNWB is an open-source C/C++ application programming interface (API) designed to enable direct data...
- This $2,576,654 Project Grant awarded by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) will support the development of a cloud-based software platform and advanced computational pipelines to harmonize and integrate spatial transcriptomics data for the construction of a spatially resolved brain atlas. Key objectives of the 3-year project include: 1) Creating a cloud-based platform to standardize the analysis and visualization of...
- Federal Project Grant Award Summary The National Science Foundation (NSF) Engineering program (CFDA 47.041) awarded The Johns Hopkins University a $2.0 million Project Grant effective August 1, 2025 through July 31, 2029 to advance organoid intelligence (OI) research through the "Bringing Reward to Embodied Organoid Intelligence" initiative. The project will develop lab-grown brain tissues engineered into three-tier brain assembloids incorporating cortical, dopaminergic, and striatal...
- Federal Cooperative Agreement Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded The Johns Hopkins University a $1,033,079 Cooperative Agreement on May 8, 2025, under the 21st Century Cures Act - Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative (CFDA 93.372) to expand training and support services for next-generation electrophysiology probe users. The award will fund at least four training classes annually through April 30, 2030,...
- Federal Project Grant Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded The Johns Hopkins University a $409,139 Project Grant on August 1, 2025, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to investigate the computational, behavioral, and neural mechanisms underlying state-driven active sensing. The research will span five years through June 30, 2030, and will examine how animals switch between...
- Federal Cooperative Agreement Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded Boston Children's Hospital a $4.1 million Cooperative Agreement under the 21st Century Cures Act - Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative (CFDA 93.372) on August 1, 2025, with completion targeted for July 31, 2028. The project, titled FAST-ET (FAST Automated Serial Tape-Enabled Electron Tomography), develops an integrated solution for...
DATAJOINT SCIOPS: A MANAGED SERVICE FOR NEUROSCIENCE DATA WORKFLOWS - PROJECT SUMMARY THIS SBIR PROPOSAL AIMS TO ADDRESS CURRENT CHALLENGES IN DATA-DRIVEN NEUROSCIENCE BY IMPLEMENTING DATAJOINT SCIOPS: A COMMERCIAL SERVICE TO HELP RESEARCH LABS IMPLEMENT COMPUTATIONAL WORKOWS FOR DATA-INTENSIVE SCIENCE EXPERIMENTS. THIS TURN-KEY SERVICE WILL ORGANIZE SECURE DATA PIPELINES AND AUTOMATE ANALYSIS JOBS BASED ON SCALABLE CLOUD INFRASTRUCTURE WHILE KEEPING THE ENTIRE PROCESS TRANSPARENT AND REPRODUCIBLE. PROGRESS IN NEUROSCIENCE RELIES ON ANALYZING VAST AMOUNTS OF COMPLEX DATA RECORDED BY NEW GENERATIONS OF NEUROTECHNOLOGIES. TO ANALYZE THIS DATA, RESEARCH TEAMS DEVELOP ADVANCED ALGORITHMS AND SHARE THEM AS OPEN-SOURCE SOFTWARE. THESE SOFTWARE TOOLCHAINS REQUIRE ADVANCED COMPUTING INFRASTRUCTURE AND OPERATIONS, POSING A SET OF ENGINEERING HURDLES TO MANAGE THE PARTICULAR EXPERIMENT WORKOWS FOR DATA ENTRY, ACQUISITION, ANALYSIS, SHARING, AND PUBLISHING. DATAJOINT SCIOPS IS MADE POSSIBLE BY THE DATAJOINT ELEMENTS PROGRAM (NIH GRANT U24 NS116470), WHICH PROVIDES A COLLECTION OF COMMUNITY-CURATED SOFTWARE MODULES FOR BUILDING STANDARDIZED COMPUTATIONAL WORKOWS. THESE DESIGNS INTEGRATE BEST-IN-CLASS OPEN-SOURCE ANALYSIS SOFTWARE FROM LEADING RESEARCH TEAMS AND PROVIDE INTEGRATIONS WITH NEUROSCIENCE INFRASTRUCTURE PROJECTS. DATAJOINT SCIOPS WILL EFFECTIVELY SERVE AS THE COMMERCIAL EXTENSION OF DATAJOINT ELEMENTS BY PROVIDING COMPUTING INFRASTRUCTURE, HOSTING, AND A MANAGED SERVICE WITH SUBJECT-MATTER EXPERT SUPPORT AND CUSTOMIZATION SERVICES. THIS DIRECT-TO-PHASE II COMMERCIALIZATION PROJECT WILL DEVELOP AND VALIDATE A COMPREHENSIVE MANAGED SERVICE FOR EXECUTING DATA-CENTRIC NEUROSCIENCE PROJECTS WITH ROBUST AUTOMATED PROCESSES FOR DATA MANAGEMENT AND ANALYSIS (AIM 1). A CLOUD-BASED SOFTWARE-AS-A-SERVICE PLATFORM WILL STREAMLINE THE SERVICE TO ENABLE SCALING TO HUNDREDS OF LABS THROUGH STANDARDIZATION, SELF-SERVICE, AND PROCESS AUTOMATION (AIM 2). IN THE PROCESS, DATAJOINT WILL PARTNER WITH JOHNS HOPKINS UNIVERSITY'S APPLIED PHYSICS LAB TO INTEGRATE THE PLATFORM WITH NEUROINFORMATICS RESOURCES AND PROVIDE COLLABORATION INTERFACES (AIM 3). JOINTLY, THE TEAMS WILL ENSURE THE TRANSPARENCY AND REPRODUCIBILITY OF THE MANAGED WORKOWS AND INTEGRATE IT WITH OTHER DATA INFRASTRUCTURE PROGRAMS IN THE U.S. AND INTERNATIONALLY. WITH SEVERAL THOUSAND NEUROSCIENCE RESEARCH GROUPS SEEKING TO ADOPT ADVANCED NEUROTECHNOLOGY INSTRUMENTS AND ANALYSIS TOOLS, THE COMMERCIALLY OPERATED DATAJOINT SCIOPS SERVICE WILL LOWER THE TECHNOLOGICAL AND ORGANIZATIONAL BARRIERS FOR EFCIENT AND REPRODUCIBLE RESEARCH. 1
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $0 | 11/13/24 | ||
| Not listed | $600.7k | 7/19/23 | ||
| Not listed | $699.3k | 6/22/22 | ||
| Not listed | $699.3k | 6/22/22 | ||
| Not listed | $385.3k | 6/22/22 |