Project Grant R44HG013067
Award Date
7/10/23
Completion Date
6/30/25
Dollars Obligated
$3.2M
Federal Agency
National Human Genome Research Institute
Federal Grant Program
93.172
Assistance Type
Project Grant
Place of Performance
South San Francisco, CA 94080, USA
Similar Awards
This Project Grant award from the National Human Genome Research Institute (NHGRI), under the Human Genome Research program (CFDA 93.172), provides $1,020,280 to Vellum Biotechnology, Inc. to develop a new nucleic acid extraction technology to enable high-quality DNA sequencing from formalin-fixed, paraffin-embedded tissue (FFPET) samples. The technology, called epitachophoresis (ETP), aims to improve the yield, quality, and length of purified nucleic acids extracted from challenging FFPET...
The National Human Genome Research Institute (NHGRI), under the Human Genome Research Federal Grant Program (CFDA 93.172), awarded a $384,418 Project Grant to Xgenomes Corp. on September 25, 2024 to develop a revolutionary DNA sequencing platform. The project aims to create a super-resolution single-molecule sequencing technology that can read short sequence "words" rather than individual nucleotides, enabling one or more orders of magnitude improvements in accuracy and cost over...
The National Human Genome Research Institute (NHGRI), under the Human Genome Research Federal Grant Program (CFDA 93.172), awarded a $1,234,692 Project Grant to Evizia Inc. for the development of a novel instrument and consumables for quality control in next-generation sequencing (NGS). Evizia's PRECYSE system utilizes high-speed atomic force microscopy to provide improved QC metrics and sensitivity for DNA sample analysis compared to traditional gel electrophoresis methods. The system enables...
This Project Grant award from the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training Program (CFDA 93.859) provides $394,857 to the University of Nebraska to develop a system to protect and concentrate large DNA molecules for genome analysis. The project aims to: Develop an inverted insert to protect DNA during cell lysis. Develop a roadblock to concentrate chromosomal DNA. The goal is to create a method to protect and concentrate large DNA molecules...
This Project Grant from the National Science Foundation's Division of Computing and Communication Foundations, under the Computer and Information Science and Engineering program (CFDA 47.070), provides $1,200,000 to the University of California, San Diego from August 1, 2022 to July 31, 2026. The award supports research into developing new coding techniques to enable DNA-based data storage. Specific objectives include establishing theoretical limits on DNA storage capacity and efficiency,...
This $653,880 Project Grant awarded by the National Human Genome Research Institute (NHGRI) under the Human Genome Research program (CFDA 93.172) supports the development of a high-content, image-based CRISPR screening platform to discover regulators of three-dimensional (3D) genome architecture across multiple length scales. The goal is to advance screening technology to enable large-scale, multi-omic analysis of the spatial organization of the genome, nucleome, and transcriptome. Key...
This R35 project grant award from the National Institute of General Medical Sciences (NIGMS) under CFDA 93.859 Biomedical Research and Research Training program provides $1,350,554 in funding to the Sloan-Kettering Institute for Cancer Research in New York, NY to conduct research on the molecular mechanisms of eukaryotic chromosome replication. The research aims to illuminate the intrinsic mechanisms of the eukaryotic DNA replication machinery and its response to diverse replication stress...
This $300,000 Project Grant from the National Science Foundation's Division of Computer and Network Systems, under the Computer and Information Science and Engineering program (CFDA 47.070), will support research to develop efficient ways to enlarge practical DNA storage capacity by integrating bio-computer technologies. Led by researchers at the University of Minnesota, the interdisciplinary team will investigate approaches to improve the scalability of DNA storage, including identifying more...
This federal Project Grant award, issued by the National Human Genome Research Institute (NHGRI) under the Human Genome Research program (CFDA 93.172), will fund the development of a new technology platform called "Expansion Genomics". The goal is to vastly improve the resolution and throughput of single-cell and spatial epigenomic analysis methods by leveraging physical expansion of biological samples. The $743,524 award to the President and Fellows of Harvard College will enable...
This $1,205,737.49 Project Grant awarded by the National Human Genome Research Institute (NHGRI) under the Human Genome Research program (CFDA 93.172) supports the development of scalable computational methods and software tools to enable better analysis and interpretation of large genomic datasets. The key objectives are to: Develop a novel maximum likelihood estimation framework and optimization techniques to significantly accelerate phylogenetic analysis and enable the use of more complex...