The National Institute of Child Health and Human Development (NICHD) awarded a $759,944 Project Grant (CFDA 93.865 - Child Health and Human Development Extramural Research) to Nextgenjane Inc., a women's health startup, to develop a non-invasive diagnostic test for endometriosis using biomarkers from menstrual effluence. This funding supports validation studies of Nextgenjane's high-performance genomic assay for endometriosis detection, with the goal of commercializing a "yes/no"...
This Project Grant award from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), provides $166,428 to the University of Arizona to study structural and functional differences in the uterotubal junction (UTJ) of women with and without endometriosis using optical coherence tomography (OCT) imaging. The key objectives are to: 1) Compare the morphology and function of explanted UTJs from...
The National Institute of Child Health and Human Development (NICHD) awarded a $173,536 Project Grant (CFDA 93.865 - Child Health and Human Development Extramural Research) to a collaborative research partnership between Henry Ford Health and Michigan State University Health Sciences. The grant aims to develop a novel, noninvasive, and early detection method for endometriosis using exhaled breath analysis. Specifically, the project will: Detect and distinguish endometriosis from healthy cells by...
This Project Grant award from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), provides $2,045,782 to Endomet Biosciences, Inc., a woman-owned small business, to advance the development and commercialization of a novel, non-hormonal therapeutic called ENDO-205 for the treatment of endometriosis. The primary objectives are to manufacture GMP clinical drug substance and product, complete...
This federal Project Grant award from the National Institute of Child Health and Human Development (CFDA 93.865 - Child Health and Human Development Extramural Research) totaling $131,085 aims to gain a better understanding of the contribution of uterine natural killer (UNK) cells to the pathobiology of endometriosis. The key objectives are to characterize the inhibitory/activating receptor repertoire and functional capacity of UNK cells from women with and without endometriosis, develop a...
This Project Grant award, provided by the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865), supports research to investigate the mechanisms underlying endometriosis pain and changes in pain following lesion removal surgery. The $233,250 award to The Washington University in St. Louis aims to study central mechanisms of inhibitory pain modulation and systemic estrogen levels, as well as...
This Project Grant award from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), provides $384,418 to Serentrix LLC to validate the efficacy of their lead compound SER-014, a TRPV1 antagonist, for the treatment of endometriosis. The award aims to 1) measure the efficacy of SER-014 in reducing pain and lesion size in a validated mouse model of endometriosis, and 2) confirm the molecular...
This Project Grant award from the National Institute of Child Health and Human Development (CFDA 93.865 - Child Health and Human Development Extramural Research) provides $2,163,115 to the University of Texas Health Science Center at San Antonio to conduct research on the genetic mechanisms underlying endometriosis severity. The 5-year project aims to characterize the epigenomic landscape of high and low stage endometriosis using single-cell multi-omics approaches, dissect allele-specific gene...
This federal Project Grant award from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), aims to investigate the implications of iron homeostasis and ferroptosis for early pregnancy and endometriosis. The $231,708 award to Baylor College of Medicine, spanning Sep 1, 2025 to Apr 16, 2028, will support research to characterize how the iron export protein SLC40A1 influences iron dynamics,...
This $275,000 Project Grant award from the National Science Foundation's (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) program supports the development of an advanced screening platform that utilizes patient-derived uterine organoids to identify therapeutic proteolysis-targeting chimeras (PROTACs) for treating uterine fibroids and endometriosis. The key objectives of this Small Business Innovation Research (SBIR) Phase I project include building a comprehensive gynecological...