Project Grant R44DA066336
- The National Institute on Drug Abuse awarded a cooperative agreement to Massachusetts General Hospital totaling $1.352 million on July 1, 2026, under the Drug Use and Addiction Research Programs (CFDA 93.279). Massachusetts General Hospital will develop an inexpensive, wearable functional near-infrared spectroscopy (fNIRS) device and integrated software to detect and assess cerebral biomarkers of drug intoxication in real-world settings. The device, designated iFlexNIRS, will feature eight...
- The National Institute on Drug Abuse awarded Pillsmart Inc. $399,993 on June 1, 2026, under the Drug Use and Addiction Research Programs (CFDA 93.279) to develop and validate the technical feasibility of LEVL, a clinical decision support system for early detection of relapse risk in adolescents with substance use disorders. LEVL integrates physiological markers (heart rate, heart rate variability, sleep), behavioral data, and environmental context into an FHIR-compliant adaptive platform that...
- The National Institute on Drug Abuse awarded SKM Instruments, Inc. $314,317 on July 1, 2026, under the Drug Use and Addiction Research Programs (CFDA 93.279) to develop a surface-enhanced Raman spectroscopy (SERS)-based lateral flow assay for rapid detection and quantification of existing and emerging illicit drugs in urine samples. The platform integrates three innovations: a SERS-active lateral flow cartridge that processes urine samples, removes interferents, and separates drug mixtures and...
- The National Institute on Drug Abuse awarded LC Acquisition LLC, doing business as Axcend LLC, $313,721 for a Phase I project grant under the Drug Use and Addiction Research Programs (CFDA 93.279) effective June 1, 2026. The award funds development and evaluation of a miniature tandem ion mobility spectrometry (IMS/IMS) detector integrated into a compact, portable capillary liquid chromatography system to detect trace amounts of novel psychoactive substances and fentanyl adulterants in bodily...
- This $586,936 Project Grant award from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) supports the development of a low-cost, disposable urine test strip that can rapidly and quantitatively measure substance use disorder (SUD) medication drugs and their metabolites. The award recipient, Vitan-Biotech LLC, will create a point-of-use lateral flow assay (LFA) test strip that leverages innovative signal amplification technology to...
- The National Institute on Drug Abuse awarded Nefer Ka LLC $311,380 on July 1, 2026, under the Drug Use and Addiction Research Programs (CFDA 93.279) to develop economical, portable detection technology for illicit drugs in bodily fluids using surface-enhanced Raman scattering (SERS). The recipient will reduce costs and improve performance of SERS-based drug detection systems through two parallel technical approaches. First, Nefer Ka will leverage its scalable production technique to lower the...
- The National Institute on Drug Abuse awarded $800,000 to Tibbling Technologies LLC on June 1, 2026, under the Drug Use and Addiction Research Programs (CFDA 93.279) to develop SmartDrive, an AI-powered mobile application for real-time detection of non-disordered drug use in drivers. SmartDrive employs a transformer-based multimodal AI framework that analyzes facial and body pose features to assess whether drivers are under the influence of drugs before operating a vehicle. The application...
- The National Institute on Drug Abuse awarded Biosyft Inc. $301,390 under the Drug Use and Addiction Research Programs (CFDA 93.279) on July 1, 2026, to develop and validate an AI-driven behavioral analysis platform for detecting addiction-like reward signatures in rodent models. Biosyft has built a multi-view chamber system with optimized computer vision models that tracks 29 points across rodents, compared to industry-standard approaches that rely on basic movement tracking or subjective...
- The National Institute on Drug Abuse awarded $314,109 to Behavior Change Hub Limited Liability Company on June 15, 2026, under the Drug Use and Addiction Research Programs (CFDA 93.279) to develop the Addiction Application Gradebook, a web platform for organizing, describing, evaluating, and tracking smartphone and web-based applications addressing substance use disorder. The Phase I Small Business Technology Transfer project will establish research and development foundations across three...
- The National Institute on Alcohol Abuse and Alcoholism awarded Creare LLC $314,357 on September 1, 2026, under the Alcohol Research Programs (CFDA 93.273) to develop a wearable sensor system for continuous monitoring of alcohol withdrawal syndrome. The project delivers a real-time bracelet-based device integrating tremor detection, heart rate variability, sleep tracking, and sweat ethanol sensing with a machine learning algorithm that synthesizes multiple physiological inputs into a continuous...
The National Institute on Drug Abuse awarded Labsys LLC $302,225 on August 15, 2026, under the Drug Use and Addiction Research Programs (CFDA 93.279) to develop a wearable Continuous Polydrug Monitor (CPM) for substance use disorder treatment. The CPM is a wearable electrochemical sensor that continuously tracks fentanyl and other high-risk substances in interstitial fluid, using computationally designed anchor molecules for drug recognition, conductive polymers for signal amplification, and electrochemical impedance spectroscopy for detection. The device integrates real-time drug monitoring with clinical decision-support systems to enable timely interventions, improve patient adherence, and expand access to evidence-based SUD treatment. Phase I research demonstrated technical feasibility of a wearable prototype; this Phase II award advances laboratory validation, regulatory alignment, and system integration for preclinical deployment. The recipient, Labsys LLC, is located in East Lansing, Michigan. The project runs through February 28, 2027.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $302.2k | 8/7/26 |