Development of an AI-empowered device that utilizes multimodal data-visualization to aid in the diagnosis, and treatment, of OUD

Active Project Grant Awarded Last action

Award ID
R44DA058431
Recipient
Awarding agency
Obligated
$1,846,160

Award facts

Assistance listing
93.279 Drug Use and Addiction Research Programs
Completion date 63% complete
Originally
Place of performance
Colorado, USA

Award details come from USAspending.gov.

Description

Abstract
Assessing the effectiveness of opioid use disorder (OUD), where high relapse rates create financial and social tolls, is a pressing clinical problem in need of better measurement tools. The ability to identify cognitive changes should improve outcomes but current intake into rehabilitation programs doesn't typically include cognitive tests. Simple, quick, cost-effective, and objective measures are needed. This is the problem this proposal seeks to address. This proposal utilizes the experience of 8 different rehab clinics which serve 150 patients weekly, and wavi, a commercialized brain-assessment platform that combines EEG evoked responses (ERP) with 5 other tests also sensitive to addiction (heart rate variability, physical reaction times, moca, trail making, and flanker). This user-friendly platform focuses on minimizing testing times and cost while maximizing information. For this fast-track application, we will have the following milestones: - collect more OUD data from different clinics to refine existing clustering algorithm and increase sensitivities and specificities so that we have a robust archetype for OUD VS healthy patients - collect follow-up OUD data and correlate follow-up scans with successful outcomes of rehabilitation treatment and therefore identify those addicts whose cognitive state requires modified treatment approaches, with the aim of decreasing relapse rates and recidivism rates. - develop a scalable multimodal product, including EEG with ERP, for rehabilitation facilities that is readily accessible to clinicians and create a dynamic data asset to help longitudinally predict outcomes.

Transactions

Action Obligated Date
Amendment $1,208,000
Amendment $0
Amendment $0
Amendment $0
Amendment $319,080
Original award $319,080

Quick answers

Who received award R44DA058431?

R44DA058431 was awarded to Wavi Co by National Institute on Drug Abuse (National Institutes of Health) on September 1, 2023.

How much is award R44DA058431 worth?

$1,846,160 has been obligated on R44DA058431.

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