Project Grant R44AG094520
- This Project Grant award from the National Institute on Aging (CFDA 93.866 Aging Research) provides $705,385 to Northeastern University to conduct a large-scale study investigating mediators and moderators of executive function training in older adults. The study aims to improve the rigor and reproducibility of research on cognitive plasticity in older adults, many of whom are at risk for Alzheimer's disease and related dementias. The study will collect data from 1,250 older adults aged 60+ to...
- The National Institute on Aging (NIA) awarded a $1,010,368 Project Grant under the Aging Research federal grant program (CFDA 93.866) to Koronis Biomedical Technologies Corp. (KBT) to develop and validate an interactive gaming platform to facilitate cognitive interventions for individuals living with mild cognitive impairment (MCI) or Alzheimer's disease and related dementias (AD/ADRD). The goal is to create an in-home cognition training system that provides evidence-based cognitive activities...
- The National Institute on Aging (NIA), under the Aging Research federal grant program (CFDA 93.866), awarded a 5-year, $210,168 project grant to the Medical University of South Carolina to support Dr. Stephanie Aghamoosa's research on developing non-pharmacological interventions for secondary prevention of dementia. The project aims to combine brain stimulation and computerized cognitive training to improve cognition in individuals with mild cognitive impairment (MCI). The research activities...
- This federal Project Grant award of $495,731.00, awarded on September 20, 2025 by the National Institute on Aging (CFDA 93.866 Aging Research program), supports the evaluation of Viewmind's ability to detect beta-amyloid and tau burden consistent with Alzheimer's disease in persons with mild cognitive impairment (MCI) using machine learning, virtual reality, and eye-tracking technology. The project aims to develop a non-invasive, cost-effective, and rapid diagnostic tool that can accurately...
- This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) provides $147,933 to the University of Florida to conduct a 5-year study investigating the effects of transcranial direct current stimulation (tDCS) on working memory performance and functional connectivity in individuals with mild cognitive impairment (MCI) compared to healthy controls. The study aims to characterize the acute (one-time) application of tDCS with standard fixed dosing on working memory...
- This federal Project Grant award of $168,775 from the National Institute on Aging (CFDA 93.866 - Aging Research) is aimed at developing a computerized cognitive remediation (CCR) intervention to treat post-viral neurocognitive dysfunction (PND) in older adults. The 5-year project, awarded to the University of Connecticut Health Center, has three key objectives: 1) examine the preliminary efficacy of the CCR intervention for improving cognitive performance and daily functioning in older adults...
- This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) in the amount of $771,627 provides funding to The Washington University to develop and evaluate a metacognitive strategy intervention for addressing cognitive decline in individuals with Parkinson's disease (PD). The long-term goal of the research is to reduce disability, improve quality of life, and delay dementia onset among people with PD by enabling them to cope with cognitive decline and perform...
- This Project Grant award of $353,391.00, provided by the National Institute on Aging (CFDA 93.866 - Aging Research), aims to validate the use of a "Personal Learning Curve" paradigm as a sensitive marker of early memory decline related to Alzheimer's disease (AD) biomarkers in a large, diverse sample of older adults. The study seeks to determine if this digital cognitive assessment tool, which measures learning over repeated evaluations, can detect subtle AD-related memory failures...
- This Project Grant award from the National Institute on Aging (CFDA 93.866 Aging Research) provides $499,686 to support the development of the Momento smartphone app. The app aims to transform regular photo activities into a way to continuously monitor cognitive function and detect early signs of memory changes in older adults. Key goals of the 1-year project include: 1) Testing how 200 older adults use and enjoy the app, ensuring it is engaging for regular use; and 2) Verifying the system can...
- The National Institute on Aging (NIA), under the Aging Research Federal Grant Program (CFDA 93.866), awarded a $6,742,946 Project Grant to the University of Michigan to evaluate the effects of personalized brain stimulation as a potential treatment for individuals with posterior cortical atrophy (PCA), which is often caused by Alzheimer's disease. The 4-year study will use functional magnetic resonance imaging (fMRI) and positron emission tomography (PET) scans to identify and target the...
This Project Grant award of $1,006,653 from the National Institute on Aging (CFDA 93.866 - Aging Research) to Posit Science Corp. supports the "IMPROVING NEUROLOGICAL HEALTH WITH ACETYLCHOLINE VIA NEUROPLASTICITY-BASED COMPUTERIZED EXERCISE IN MILD COGNITIVE IMPAIRMENT (INHANCE-MCI)" program. The project aims to deploy a computerized cognitive training program that integrates validated exercises to potentially reduce the long-term risk of dementia onset in individuals with mild cognitive impairment. The broader objectives are to uncover the mechanisms through which specific brain training can deliver cognitive and functional gains, as well as promote widespread availability of the program across web, iOS, and Android platforms on both internet-connected and offline devices. This prospective, double-blind, parallel-arm, active-controlled clinical trial will randomize patients to the intervention or active control and evaluate changes in cholinergic function, cognitive performance, and functional abilities.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $1.0m | 9/18/25 |