Project Grant R43TR004754
Award Date
5/22/24
Completion Date
5/23/25
Dollars Obligated
$350K
Federal Agency
National Center for Advancing Translational Sciences
Awardee
Vivosphere LLC (QSAGDTU231N8)
Federal Grant Program
93.350
Assistance Type
Project Grant
Place of Performance
Alabama, USA
Similar Awards
This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Phase I Small Business Technology Transfer (STTR) project grant, awarded to Vivosphere LLC, is developing a novel 3D tissue-engineered platform for cancer modeling and high-throughput drug screening. The $275,000 project aims to create a more physiologically relevant and scalable system to improve the translation of preclinical cancer drug candidates to clinical trials. Key objectives include testing...
This Project Grant awarded by the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training federal grant program (CFDA 93.859), aims to advance the commercialization of an innovative automated cell culturing system. The $295,038 award to Altvivo, Inc. will enable the development of capabilities to: 1) induce different cell lineages from stem cells via localized drug delivery to achieve complex tissue patterns; and 2) perform non-disruptive...
The National Center for Advancing Translational Sciences (NCATS), through its CFDA 93.350 Federal Grant Program, awarded a $294,541 Project Grant to Cellular Vehicles Inc. on June 1, 2024. The purpose of this award is to develop an automated system for producing and delivering cell-laden hydrogel therapies. The project aims to create a novel, standardized process for formulating, encapsulating, and directly injecting cell-laden hydrogels into diseased tissues. This is intended to improve the...
This $750,000 Project Grant was awarded on April 15, 2025 by the National Science Foundation's (NSF) Division of Molecular and Cellular Biosciences under the Biological Sciences (CFDA 47.074) Federal Grant Program. The grant will fund research at the University at Albany, SUNY to develop manufacturable 3D mammalian cell culture systems focused on neural organoids with integrated sensing technologies. Key objectives include: (1) building and testing conformal microelectrode arrays to...
The National Center for Advancing Translational Sciences (NCATS), a part of the National Institutes of Health, awarded a $349,952 Project Grant (CFDA 93.350) to Intero Biosystems Inc. on June 20, 2025. The grant aims to develop and validate a novel human intestinal organoid (HIO) screening platform for preclinical drug discovery and testing. The HIO system is designed to better mimic human intestinal physiology compared to traditional cell monolayers or animal models, with the goal of...
This Project Grant award from the National Center for Complementary and Integrative Health (NCCIH), under the federal Research and Training in Complementary and Integrative Health program (CFDA 93.213), provides $306,793 to Vivoverse, LLC, a woman-owned small business in Austin, Texas, to develop an automated high-throughput screening platform using the C. elegans model organism. The project aims to create imaging-based assays to assess the effects of natural products, including plant extracts...
This Project Grant award from the National Science Foundation (CFDA 47.084 - NSF Technology, Innovation, and Partnerships) provides $303,864 to Core Biotherapeutics Inc. to develop a platform for discovering therapeutic drugs that can reprogram molecular networks to treat diseases. The project aims to determine the biological laws driving diseases at the molecular network level and create an algorithm to rapidly identify drug targets. The key goals are to demonstrate that oligonucleotide drug...
This Project Grant award from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training Program (CFDA 93.859), is focused on developing a novel high-throughput, high-content imaging platform for analyzing extracellular vesicles (EVs) at the single-particle level. The $298,999 award to Numentus Technologies Inc. will fund the construction, testing, and application of this platform to detect and characterize EV subpopulations, including...
The National Science Foundation Division of Industrial Innovation awarded $255,478 under the Engineering (47.041) federal grant program to Crossmhv, L.l.c. (doing business as Nascence) for the project "STTR PHASE I: RAPID-RELEASE CELL CULTURE PLATFORM FOR FLOW CYTOMETRY." The one-year project period runs from January 1, 2022 to December 31, 2022. Under this Project Grant, Nascence will develop a rapid-release cell culture platform to enable high-throughput flow cytometry analysis....
This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant of $274,829 awarded to Rosebud Biosciences Inc. on August 15, 2023 aims to enable the development of new therapies for rare diseases in children. The project objectives are to: (1) Automate the derivation of heart, liver, and brain organoids from human stem cells, and (2) Develop automated machine learning models to detect disease phenotypes in these organoids derived from patients with...