Cooperative Agreement R43OH012129

Federal Grant Award Summary Flexbiotech Inc. received a $306,872 Small Business Innovation Research (SBIR) Phase I grant from the National Cancer Institute under the Cancer Detection and Diagnosis Research Program (CFDA 93.394) awarded on September 1, 2025, with a completion date of August 31, 2026. The award supports the development and commercialization of SPRINT-HPV (Simple, Portable, and Rapid Isothermal Nucleic-Acid Test), a portable molecular screening device designed for point-of-care...

Federal Grant Award Summary Optimeos Life Sciences, Inc. received a Phase I Small Business Innovation Research (SBIR) grant of $300,000 from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded on August 19, 2025, with completion scheduled for July 31, 2027. The project deliverables focus on developing an off-the-shelf nanoparticle platform for in vivo stem cell gene therapy to treat adenosine...

Federal Grant Award Summary Innotech Precision Medicine, Inc., a woman-owned and minority-owned small business, received a $1.414 million Project Grant from the National Institute of Dental and Craniofacial Research (NIDCR) under the Oral Diseases and Disorders Research program (CFDA 93.121). The award, issued on August 8, 2025, supports the Phase II development of RECOGNIZE-OPSCC, a saliva-based, point-of-care diagnostic test designed to detect oropharyngeal squamous cell carcinoma (OPSCC)...

Federal Grant Award Summary Sunflower Therapeutics PBC received a $306,347 Project Grant award from the National Institute of Allergy and Infectious Diseases under the Allergy and Infectious Diseases Research program (CFDA 93.855) on August 21, 2025. This Fast-Track Small Business Innovation Research (SBIR) Phase I award supports the development of an automated, continuous cell disruption system integrated with a bioreactor platform for cost-effective manufacturing of virus-like particle (VLP)...

This SBIR Phase I project, awarded by the National Science Foundation (NSF) under the Technology, Innovation, and Partnerships (CFDA 47.084) program, is focused on the development of a novel mammalian cell-based nano-biological coating for implantable medical devices. The goal is to address the critical health and economic burden associated with implant-related infections by reducing or eliminating them through the use of this biocompatible and antimicrobial nano-biological coating. The $305,000...

Federal Project Grant Award Summary Cleaved Diagnostic Corporation received a $305,000 Small Business Technology Transfer (STTR) Phase I award from the National Science Foundation (NSF) Technology, Innovation, and Partnerships program (CFDA 47.084) effective October 1, 2025 through September 30, 2026. The company will develop a one-step molecular diagnostic platform utilizing Clustered Regularly Interspaced Short Palindromic Repeats-associated protein 12A (CRISPR-Cas12a) technology to detect...

Federal Grant Award Summary Nanoplasmonics LLC received a $304,780 Phase I Small Business Innovation Research (SBIR) award from the National Science Foundation (NSF) Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084) on June 1, 2025, to develop breakthrough sensor technology for mycotoxin detection in the food supply chain. The project, based in Colorado Springs, Colorado, will be completed by May 31, 2026. The primary deliverable is an innovative detection system that...

This SBIR Phase I Project Grant, valued at $305,000.00 and awarded by the National Science Foundation (NSF) under the Technology, Innovation, and Partnerships (CFDA 47.084) program, aims to develop a novel class of peptide-based compounds capable of safely and effectively treating autoimmune and inflammatory disorders, including rare diseases affecting pediatric populations. The project will demonstrate the unique design of these compounds to modulate immune responses from pro- to...

This SBIR Phase I award from the National Science Foundation (NSF) under the NSF Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084) provides $273,550 to Biocognon LLC for the development of a combinatorial platform to discover improved molecular recognition components for use in therapeutic and diagnostic antibodies. The project aims to utilize synthetic biology, next-generation DNA sequencing, and computational biology to efficiently generate and screen libraries of antibody...

Federal Grant Award Summary Scanogen Inc., a minority-owned small business, received a $969,449 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) on September 17, 2025, with a completion date of August 31, 2028. The award funds a Commercialization Readiness Pilot program to advance an automated diagnostic platform for rapid yeast bloodstream infection detection directly from whole...