Office of the Director

The Centers for Disease Control and Prevention, a sub-agency of the Department of Health and Human Services, administers federal grant funding for public health research, disease surveillance, prevention programs, and behavioral intervention initiatives. CDC has awarded 192 federal grants totaling $490.2 million in federal dollars obligated since 2010, with recent activity declining across the last five years: 31 awards in 2022, 31 in 2023, 18 in 2024, 12 in 2025, and 13 year-to-date in 2026. The most recent grant award closed on 2026-09-30.

Grant recipients are highly fragmented. The top five recipients by award count over the last five years hold only 14 percent of recent awards, each securing three awards: Klein Buendel, Inc. ($1.2 million federal dollars), Nanohmics Inc. ($2.8 million), Creare LLC ($5 million), Seacoast Science, Inc. ($2.6 million), and Oregon Research Behavioral Intervention Strategies, Inc. ($5.9 million). By federal dollar value, concentration remains minimal at 4 percent of recent funding, with Oregon Research Behavioral Intervention Strategies, Inc., Creare LLC, Empowerx, Inc., Charles River Analytics, Inc., and Minnesota Healthsolutions Corporation leading. Across the portfolio history, 147 distinct recipients have received awards, underscoring broad dispersion. CDC has obligated a combined total of $495.4 million (federal and non-federal share combined).

CDC structures its grant portfolio as predominantly Project Grants (91 awards, 47 percent) and Cooperative Agreements (75 awards, 39 percent), with Formula Grants accounting for 26 awards (14 percent). The Project Grant and Cooperative Agreement split reflects CDC's dual focus on time-limited research and innovation alongside longer-term partnership models with state and local health departments and community organizations. Most recent grant opportunity information is not recorded against CDC or its descendant offices.