Project Grant R43HG008926

This Project Grant award from the National Science Foundation (NSF) under the Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084) supports the development of an autonomous, miniaturized system for DNA extraction and preparation for sequencing. The $275,000 award to Anyglabs, Inc. will fund the creation of a portable, automated device capable of high-throughput DNA processing in space and other austere environments. The goal is to democratize access to advanced molecular...

Micropure Genomics Inc. received a $274,199 Project Grant award from the National Science Foundation to advance methods for rapid, end-to-end sample preparation for sequencing applications. Under the NSF Technology, Innovation, and Partnerships program (CFDA 47.084), the company will develop an automated process relying on electro-hydrodynamic trapping to isolate genomic material like DNA or RNA from cells in a flow cartridge. The process aims to significantly reduce preparation time while...

This $255,991 National Science Foundation project grant supports the development of an automated system for rapid analysis of biopsy samples by Amcyt, Inc. The system aims to increase the efficiency and accessibility of fine needle aspiration biopsy procedures through three automated processes: sample smearing, staining, and image capture. This addresses a critical need to improve biopsy analytics and potentially eliminate up to 20% of failed procedures due to sampling errors. By automating...

This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award supports the development of a novel device that can rapidly and automatically extract pathogen DNA from whole blood samples to enable faster diagnosis of sepsis. The $274,858 award to New England Hemolytics, Inc., with a project period from September 1, 2024 to February 28, 2025, will fund the testing and optimization of this technology across common sepsis-causing pathogens. The...

FIND-SEQ Cell Sorting Technology Development and Commercialization The National Institute on Aging awarded Vivid Bioinnovations, PBC (operating as Fluid Discovery, Inc.) a $613,742 Project Grant under the Aging Research program (CFDA 93.866) on September 12, 2025, with a completion date of February 28, 2027. This Fast-Track Small Business Innovation Research (SBIR) award supports the translation and commercial development of FIND-SEQ, a novel cell sorting technology that enables isolation of...

Federal Grant Award Summary Avant Genomics, Inc. received a $305,000 Small Business Innovation Research (SBIR) Phase I project grant from the National Science Foundation (NSF) under the Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084), awarded October 1, 2025, with a completion date of September 30, 2026. The company is developing an automated microfluidic-based system that streamlines bisulfite conversion, a critical and time-consuming step in preparing circulating tumor DNA...

This $256,000 National Science Foundation Engineering grant supports the development of an easy RNA adenylation method for deep sequencing of picogram RNA samples with high resolution. Specifically, Ezrabio Inc. will develop a versatile and cost-effective library construction technology that enables protein translation monitoring on a variety of biological samples. The proposed technology relies on a novel enzyme system capable of 5' adenylation and 3' polyadenylation of RNA fragments to...

This National Science Foundation (NSF) Small Business Innovation Research (SBIR) Phase I award to RT Microdx Inc. provides $274,362 to develop a novel molecular diagnostic platform for detecting respiratory diseases like strep throat. The platform aims to provide laboratory-quality accuracy for at-home use by non-healthcare professionals. Key technical objectives include optimizing the sensitivity of the platform's pH-sensitive polymer detection mechanism and ensuring robust performance at...

Armonica Technologies, Inc. was awarded a $1,047,600 Project Grant from the National Human Genome Research Institute of the Department of Health and Human Services to develop a novel DNA sequencing platform. The award was made under the Human Genome Research program (CFDA 93.172), which supports technologies to accelerate genomic research and its application to human health. Specifically, Armonica will use the funding to optimize a metal-insulator-metal structure for single base sensitivity...

This Project Grant award from the National Institutes of Health's National Human Genome Research Institute provided $768,678 to Molecular Assemblies, Inc. to develop a fully enzymatic oligonucleotide synthesis cycle using engineered template-independent polymerases and a novel phosphate dNTP blocking group. The award supports the goals of the Human Genome Research program (CFDA 93.172) to accelerate genome research and its application to human health. Specifically, the awardee will engineer...