Project Grant R43HD114347
- The University of North Carolina at Chapel Hill received a $100,000 Project Grant award from the National Science Foundation under the NSF Technology, Innovation, and Partnerships program (CFDA 47.084) to develop a digital therapeutic device and mobile application for patients with high-tone pelvic floor disorders. The award will support the creation of an interactive pelvic wand and accompanying smartphone app to enable patients to conduct targeted pelvic floor muscle physical therapy...
- This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Drug Use and Addiction Research Programs (CFDA 93.279), provides $1,516,765 to the University of California, Los Angeles (UCLA) to develop and validate an innovative near-infrared spectroscopy (NIRS) technology for the quantitative assessment of pelvic floor muscle function in patients with myofascial pelvic pain (MPP). The research aims to establish NIRS as an effective, non-invasive,...
- This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) supports the development of an ultrasound-coupled electrical impedance tomography (US-EIT) device for assessing sarcopenia, a condition involving loss of skeletal muscle mass and function. The $275,762 award to Rytek Medical Inc. will be used to design a sonolucent electrode array and housing that integrates with a standard ultrasound probe, enabling quantitative evaluation of muscle health through...
- The Project Grant awarded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), is focused on developing a novel shape-changing midurethral sling device to treat stress urinary incontinence in women. The $1,429,924 award to Texas A&M Engineering Experiment Station (Tees) aims to fabricate and characterize magnetic elastomer slings that can dynamically support and...
- This federal Project Grant award of $294,886, awarded on August 15, 2025 by the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), aims to develop a wearable, non-invasive ultrasound device to monitor urine output. The goal is to create an automated measurement platform that can accurately monitor organ function and transform the management of patients undergoing...
- This Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB), under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), provides $206,132.00 to the University of Houston System to develop a wireless, battery-free bioelectronic implant capable of monitoring and modulating bladder function in patients with spinal cord injury. The goal is to create an artificial intelligence-powered closed-loop...
- This federal Project Grant award from the National Institute of Child Health and Human Development (CFDA 93.865 - Child Health and Human Development Extramural Research) provides $303,000 to Saint Louis University to develop a small animal tensiometer for noninvasively measuring in vivo muscle forces and to evaluate the effectiveness of electrically stimulated eccentric contraction (ESEC) training on improving muscle function following volumetric muscle loss (VML) injury in a rodent model. The...
- The National Institute of Neurological Disorders and Stroke (NINDS), part of the National Institutes of Health (NIH), awarded a $769,846 Project Grant under the Drug Use and Addiction Research Programs (CFDA 93.279) to Lumina Medical LLC in California. The grant will fund the development of an "Innovative Vaginal Girth Adjustable Dilator with Precise Dilation Monitoring" designed to improve pain management for patients with pelvic floor disorders. The innovative technology enables...
- This Project Grant award of $87,078 from the National Institute of Biomedical Imaging and Bioengineering (NIBIB), under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), aims to develop a wearable, AI-integrated, multimodal uterine monitoring system. The system will capture both electrical activity and mechanical contractions of the uterus to provide a more comprehensive understanding of uterine activity during pregnancy and labor....
- This $1,268,662 Project Grant award from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) aims to advance the understanding and prevention of pelvic organ prolapse (POP) in women. The project will use MRI, clinical measures, and RNA sequencing to quantify the structural, functional, and cellular/molecular characteristics of the pelvic floor, with the goal of...
DEVELOPMENT OF AN ELECTRICAL IMPEDANCE MYOGRAPHY (EIM) VAGINAL DEVICE FOR THE EVALUATION OF PELVIC SKELETAL MUSCLES - 1 ABSTRACT 2 BOLD TYPE IS DEVELOPING THE "SENSEWAND", A WIRELESS PELVIC FLOOR DIAGNOSTIC SYSTEM (DEVICE AND APP) 3 TO EVALUATE PELVIC FLOOR MUSCLE HEALTH USING ELECTRICAL IMPEDANCE MYOGRAPHY (EIM). PFDS ARE COMPLEX 4 CONDITIONS (E.G. PELVIC ORGAN PROLAPSE, STRESS URINARY INCONTINENCE, HIGH TONE PELVIC FLOOR DYSFUNCTION) THAT IMPACT 5 MILLIONS OF WOMEN WORLDWIDE. IT IS ESTIMATED THAT PFDS WILL AFFECT UP TO 50% OF WOMEN OLDER THAN 50 YEARS. RISK 6 FACTORS INCLUDE PREGNANCY, CHILDBIRTH, OBESITY, AGING, AND GENETIC PREDISPOSITION, THOUGH THE PATHOGENESIS 7 CONTINUES TO BE POORLY UNDERSTOOD. CONSEQUENTLY, PFDS ARE ASSOCIATED WITH SIGNIFICANT HEALTH CARE EXPENDITURE 8 DUE TO LACK OF PREVENTIVE MEASURES, HIGH FAILURE RATE OF CURRENT INTERVENTIONS, AND THE NEED FOR RETREATMENTS. THE 9 SKELETAL PELVIC FLOOR MUSCLES (PFMS) SUPPORT THE PELVIC AND ABDOMINAL VISCERA AND INJURY AND DYSFUNCTION PLAY A 10 ROLE IN PFDS. THESE DISORDERS REQUIRE CONSIDERABLE ONGOING EVALUATION TO BE MANAGED EFFECTIVELY IN SYMPTOMATIC 11 PATIENTS. CURRENT DIAGNOSTIC METHODS ARE LIMITED, AND NO NONINVASIVE DIAGNOSTIC METHODS ARE AVAILABLE TO 12 EVALUATE PFM QUALITY. SPECIFICALLY, WE CURRENTLY LACK DIAGNOSTIC TOOLS TO HELP CLINICIANS BETTER DIAGNOSE 13 AND TREAT PATIENTS WITH PFDS. 14 WE PROPOSE DEVELOPMENT AND EVALUATION OF THE "SENSEWAND", A WIRELESS PELVIC FLOOR DIAGNOSTIC SYSTEM 15 (DEVICE AND APP) TO EVALUATE PELVIC FLOOR MUSCLE HEALTH USING EIM. EIM APPLIES WEAK, NON-DETECTABLE, 16 MULTIFREQUENCY ELECTRICAL CURRENTS TO A MUSCLE (OR MUSCLE GROUP) THROUGH TWO EXCITATION ELECTRODES, AND RESULTING 17 VOLTAGES ARE MEASURED VIA TWO SENSE ELECTRODES. MEASUREMENTS ARE FAST (
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $0 | 7/15/25 | ||
| Not listed | $0 | 9/28/23 | ||
| Not listed | $384.6k | 9/25/23 |