Project Grant R43DA065300
- Federal Project Grant Award Summary Oregon Health & Science University received a $905,044 Project Grant from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279), awarded May 1, 2026, with completion scheduled for April 30, 2028. The award funds a mixed-methods research study examining current assessment practices and documentation of electronic nicotine delivery systems (ENDS) use in primary care settings across 22 clinics serving...
- Federal Project Grant Award Summary The National Institute on Drug Abuse (NIDA) awarded a Project Grant totaling $142,003 to the University of California Irvine on October 9, 2025, under the Drug Use and Addiction Research Programs (CFDA 93.279). This three-year research initiative, which concludes on September 30, 2028, investigates the interaction between nicotine and G-protein coupled receptor 3 (GPR3) to advance nicotine cessation therapeutics. The project addresses critical gaps in...
- Federal Project Grant Award Summary The National Institute on Drug Abuse (NIDA) awarded a $144,372 Project Grant to Washington University on May 15, 2026, through the Drug Use and Addiction Research Programs (CFDA 93.279) to support research on the implementation speed and scale-up of personalized tobacco use treatment. The award funds a Mentored Career Development (K02) grant for a recently tenured investigator conducting research that bridges precision medicine and implementation science....
- Federal Grant Award Summary The University of Nebraska Medical Center (UNMC) received a $422,125 Project Grant from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279), awarded July 1, 2026, with completion targeted for June 30, 2028. The grant funds epidemiological research examining oral nicotine pouch (ONP) use and associated health effects among adolescents (ages 12-17) and young adults (ages 18-24) in the United States. The research...
- Federal Project Grant Award Summary Praeventix LLC received a $355,190 Project Grant from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279), awarded June 1, 2026, with an ultimate completion date of May 31, 2027. The grant funds in vivo characterization studies of 5-HT7 modulators, specifically the lead compound PRA078, in rat models of opioid use disorder (OUD). The research evaluates how antagonism of the 5-HT7 receptor regulates...
- Federal Project Grant Award Summary The National Institute on Drug Abuse (NIDA) awarded the University of Oklahoma Health Sciences Center a $2.23 million Project Grant under the Drug Use and Addiction Research Programs (CFDA 93.279) to conduct a five-year research initiative examining the addiction potential, flavoring content, and substitutability of concept-flavored cigarillos among young adults aged 18–24. The award, obligated on August 1, 2025, with completion targeted for May 31, 2030,...
- Federal Grant Award Summary West Virginia University received a $931,766 Project Grant from the National Institute on Drug Abuse under the Drug Use and Addiction Research Programs (CFDA 93.279) effective August 1, 2025, through July 31, 2028. The project, "Evaluation of Dependence and Nicotine Replacement Therapy-Supported Cessation Efforts Among Regular Electronic Cigarette Users," addresses a critical gap in research regarding electronic cigarette (e-cigarette) dependence and...
- Federal Grant Award Summary The University of Kansas Medical Center Research Institute, Inc. received a $690,741 Project Grant from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279), awarded June 15, 2026, with completion targeted for March 31, 2031. This research project evaluates the impact of synthetic cooling agent cigarettes on smoking behavior and abuse liability among adults who smoke menthol cigarettes, with direct implications...
- Federal Project Grant Award Summary The National Institute on Drug Abuse (NIDA) awarded $247,878 to the University of Texas at Arlington (UTA) under the Drug Use and Addiction Research Programs (CFDA 93.279) to conduct a comprehensive research study examining waterpipe tobacco smoking and its public health implications. The award, effective May 1, 2026 through April 30, 2028, supports a 2x2 crossover study involving 60 young adult waterpipe smokers aged 21-39 years to investigate how waterpipe...
- Federal Grant Award Summary The National Institute on Drug Abuse (NIDA) awarded a $742,500 Project Grant (R34) to Massachusetts General Hospital on July 15, 2025, under the Drug Use and Addiction Research Programs (CFDA 93.279). This three-year pilot study, concluding June 30, 2028, will develop and test a peer recovery coaching intervention designed to promote tobacco abstinence in individuals with concurrent opioid use disorder and tobacco use disorder (MOUD-TUD). The project will adapt an...
Scientific Horizons Consulting LLC received a $399,250 Project Grant from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) for the period July 1, 2026 through June 30, 2027. The award funds development and optimization of Water Inhalable Nicotine (WIN), an innovative orally inhaled nicotine replacement therapy (NRT) designed to improve smoking cessation outcomes. WIN features a cartridge-based design with a proprietary water formulation, intelligent dose algorithm integrated into a mobile application, and a color-coded step-down treatment regimen to support personalized cessation strategies while minimizing inhalation toxicity and environmental impact. Under Aim 1, the grantee will optimize WIN's design across three nicotine strength formulations (high, medium, and low) through comprehensive aerosol and chemical characterization testing. Key deliverables include quantification of nicotine emissions under varied conditions, analysis of aerosol particle size for optimal lung deposition, and assessment of harmful constituents including carbonyls, volatile organic compounds, and heavy metals to confirm safety and efficacy. This research addresses a significant market gap, as no FDA-approved inhaled NRTs currently exist despite regulatory support for innovative cessation solutions and superior pharmacokinetics compared to conventional nicotine replacement therapies.Federal Project Grant Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $399.3k | 6/23/26 |