The National Institute on Drug Abuse (NIDA) awarded Attune Neurosciences, Inc. a $399,739 Project Grant under the Drug Use and Addiction Research Programs (CFDA 93.279) to develop a head-worn low-intensity focused ultrasound (LIFU) device for enhancing sleep in individuals with substance use disorder (SUD), including opioid use disorder (OUD). The project aims to reconfigure Attune's existing head-worn LIFU device to improve the form factor and usability, followed by a 7-night usability study with participants from an outpatient addiction treatment facility. The research aims to create a wearable headband-style device that can ultimately be used to treat multiple aspects of addiction, such as drug craving and underlying sleep disorders, by delivering precise ultrasound stimulation to specific brain regions. This non-pharmacological intervention is intended to address the critical unmet need for new treatments to improve sleep quality and prevent relapse in individuals recovering from addiction.
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