NGS based metagenomic screening of ocular infections
Active Project Grant Awarded Last action
- Award ID
- R42EY033266
- Recipient
-
Chromologic LLC UEI D9EVNTKKWLF3
- Awarding agency
-
National Eye Institute
National Institutes of Health, Department of Health and Human Services
- Obligated
- $4,397,020
Award facts
- Assistance listing
- 93.867 Vision Research
- Completion date 84% complete
- Originally
- Place of performance
- Monrovia, CA 91016, USA
Award details come from USAspending.gov.
Description
- Abstract
- The project objective is to develop an organism-agnostic deep sequencing-based diagnosis of ocular infectious disease from microliter-sized biopsies in less than 24 hours and for less than $1000. Current diagnostic approach relies on bacterial and fungal cultures that are time-consuming (~2-3 days) and often leads to the overuse of broad-spectrum antibiotics. In phase i, we successfully developed and validated the eye-path™ system, demonstrating an integrated scalable metagenomics alignment research tool (smart) with an automated DNA extraction system for sample preparation. This system achieved a low limit of detection (104 cells/ML) and a turnaround time of
Transactions
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| Amendment | $898,365 | |
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| Original award | $803,560 |
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Quick answers
Who received award R42EY033266?
R42EY033266 was awarded to Chromologic LLC by National Eye Institute (National Institutes of Health) on June 1, 2022.
How much is award R42EY033266 worth?
$4,397,020 has been obligated on R42EY033266.
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