Feasibility of APP-delivered circadian synchronization therapy with light in a cohort of pregnant women
Ended Project Grant Awarded Last action
- Award ID
- R41HD114317
- Recipient
-
Arcascope Inc. UEI CFZ7HKGZN762
- Awarding agency
-
National Institute of Child Health and Human Development
National Institutes of Health, Department of Health and Human Services
- Obligated
- $295,128
Award facts
- Assistance listing
- 93.865 Child Health and Human Development Extramural Research
- Completion date
- Originally
- Place of performance
- Virginia, USA
Award details come from USAspending.gov.
Description
- Abstract
- Circadian rhythms play a vital role in promoting maternal health and managing pregnancy outcomes, including gestational diabetes, preterm birth, and postpartum depression. However, interventions to mitigate circadian rhythms disruption during pregnancy are lacking, despite readily available non-pharmacological circadian interventions. The circadian timekeeping system is strengthened and aligned to the 24-hour day by light, and environmental light manipulations can shift the phase and alter the amplitude of circadian rhythms when based on careful timing and combined with other behaviors. This phase I sttr project aims to evaluate the feasibility of circadian synchronization therapy with light (CST-L) in a socioeconomically diverse population of pregnant women. The intervention involves bright light exposure at specific times to phase advance, delay, or boost the amplitude of the circadian clock, DIM light at other times, as well as the use of a diary to track the causes of circadian disruption. To evaluate the success of the trial, we will collect subjective feedback from 20 pregnant women using the APP and blue-blocking glasses for four weeks, and will make iterative updates to the APP in response to user feedback. The ultimate goal is to develop a mobile application for both IOS and android that delivers CST-L and helps improve maternal mood and health, as well as infant sleep training. If successful, this intervention could help reduce the risk of preterm birth, postpartum depression, and other poor outcomes during and after pregnancy.
Transactions
| Action | Obligated | Date |
|---|---|---|
| Amendment | $0 | |
| Original award | $295,128 |
Quick answers
Who received award R41HD114317?
R41HD114317 was awarded to Arcascope Inc. by National Institute of Child Health and Human Development (National Institutes of Health) on September 11, 2023.
How much is award R41HD114317 worth?
$295,128 has been obligated on R41HD114317.
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