Project Grant R41HD104296

Award Date 8/1/21
Completion Date 1/31/24
Dollars Obligated $770K
Federal Grant Program
93.865
Assistance Type
Project Grant
Place of Performance
Irvine, CA 92614, USA
Similar Awards
This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) provides $1,901,570 to Flint Rehabilitation Devices, LLC to develop and evaluate the MIGO TRACKER, a remote therapeutic monitoring system for post-stroke rehabilitation. The key products and services to be delivered under this award include: Completing the firmware development of the MIGO TRACKER wearable sensor based on end-user feedback. The MIGO TRACKER seamlessly monitors adherence to home exercise...
This federal Project Grant award from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), aims to develop a robust, wireless, and engaging rehabilitation system to improve post-stroke gait and leg function. The total award amount is $1,379,072, with a project period from August 1, 2024 to July 31, 2029. The key products and services to be delivered under this grant include: Developing a...
This $1,149,995.00 Project Grant award from the National Science Foundation (NSF) Computer and Information Science and Engineering (CISE) Program (CFDA 47.070) supports research at New York University (NYU) School of Medicine to develop innovative methods in artificial intelligence (AI) and motion capture technology to analyze patient movement and improve stroke rehabilitation. The key objectives of the project are to: 1) develop a method to integrate multimodal data into a shared representation...
The National Science Foundation (NSF) awarded a $550,000 Project Grant under the NSF Technology, Innovation, and Partnerships program (CFDA 47.084) to the University of Pittsburgh to develop a visual unilateral neglect detection, assessment, and rehabilitation tool for stroke patients. The project will incorporate augmented reality and electroencephalography technologies to objectively quantify neglect severity and provide tailored sensory stimulation during everyday activities. This aims to...
This Project Grant award from the National Institute of Child Health and Human Development (CFDA 93.865 - Child Health and Human Development Extramural Research) totaling $465,840 aims to develop and clinically evaluate an innovative closed-loop functional electrical stimulation (FES) control system to improve post-stroke gait in individuals with foot drop. The key product is a leading-edge FES neuroprosthetic technology that uses ultrasound sensing and model predictive control to optimize FES...
This federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, provides $652,497 to The General Hospital Corporation (doing business as Massachusetts General Hospital) to conduct a research study on stroke-induced proximal upper extremity motor control impairment and rehabilitation. The key objectives of this 5-year project are to: (1)...
This National Science Foundation project grant of $346,369 will fund the development of a novel gait training method for individuals after stroke from October 1, 2022 to September 30, 2025. The funding supports Syracuse University under the NSF Engineering Directorate's program to improve quality of life and economic strength through engineering innovation. Specifically, the grant will advance knowledge on enhancing muscle power and propulsion, a key barrier to improved walking after stroke. The...
This Project Grant award from the National Institute of Child Health and Human Development (CFDA 93.865 - Child Health and Human Development Extramural Research program) to the Rehabilitation Institute of Chicago (doing business as Shirley Ryan AbilityLab) aims to develop neuromodulatory strategies to improve paretic leg motor control during walking in individuals with stroke. The $148,568 award, with a project period from May 2025 to November 2026, will investigate the effects of transcutaneous...
This Project Grant award from the National Institute of Child Health and Human Development (CFDA 93.865 - Child Health and Human Development Extramural Research) provides $584,259 to Emory University to evaluate the efficacy and sustainability of a carepartner-integrated telerehabilitation program for persons with stroke. The overarching goal is to optimize stroke recovery by developing family-centered rehabilitation interventions that support continued functional improvements in stroke...
This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) aims to conduct a large-scale randomized clinical trial to evaluate the efficacy of a wearable surface electromyography (sEMG) biofeedback sensor technology, called i-Phagia, as an adjunct to both in-person and telehealth swallow therapy protocols for patients with chronic stroke or Parkinson's disease and dysphagia (oropharyngeal swallowing disorders). The $549,106 award, provided to Purdue...

MIGO: WEARABLE SENSORS THAT COMBINE ACTIONABLE DATA WITH A BEHAVIORAL INTERVENTION TO IMPROVE FUNCTION AFTER STROKE - ONE OF THE MOST IMPENETRABLE PROBLEMS CHALLENGING FULL RECOVERY AFTER STROKE IS THE GAP BETWEEN MOTOR CAPACITY THAT A STROKE SURVIVOR REGAINS (I.E. WHAT THEY CAN DO) AND HOW THEY ENGAGE IN HOME AND COMMUNITY ACTIVITIES (I.E. WHAT THEY CHOOSE TO DO). TO ADDRESS THIS CHALLENGE, FLINT REHAB DEVELOPED MIGO, A NOVEL MULTI-SENSOR ACTIVITY TRACKER SPECIFICALLY DESIGNED FOR STROKE SURVIVORS. THE UNIQUE FEATURE OF MIGO IS THE ABILITY TO CAPTURE AND DELIVER FEEDBACK ON BOTH QUANTITATIVE AND QUALITATIVE UPPER AND LOWER LIMB ACTIVITY OF STROKE SURVIVORS IN THEIR NATURAL ENVIRONMENT USING THE SAME SYSTEM. THE LONG-TERM GOAL FOR THIS PROJECT AND THE MIGO TECHNOLOGY IS TO DEVELOP A DATA-DRIVEN AND CLINICALLY INFORMED BEHAVIORAL INTERVENTION STRATEGY THAT USES ACTIONABLE QUANTITATIVE AND QUALITATIVE FEEDBACK TO MAXIMIZE PHYSICAL FUNCTION AFTER STROKE. THIS PROJECT COMBINES FLINT REHAB'S TECHNOLOGY FOR REAL-TIME MOTION CAPTURE AND EXPERTISE IN DEVELOPING NEUROREHABILITATION DEVICES WITH THE EXTENSIVE EXPERIENCE IN STROKE NEUROREHABILITATION OF THE MOTOR BEHAVIOR AND NEUROREHABILITATION TEAM AT THE UNIVERSITY OF SOUTHERN CALIFORNIA. THIS PHASE I STTR AIMS TO ESTABLISH THE FEASIBILITY, VALIDITY, ACCURACY AND USABILITY OF MIGO TO MONITOR FUNCTIONAL MOVEMENT BEHAVIORS AND DELIVER MEANINGFUL FEEDBACK TO STROKE SURVIVORS ACROSS A BROAD RANGE OF MOTOR IMPAIRMENTS SEEN IN THIS POPULATION (AIM 1). SPECIFICALLY, 30 INDIVIDUALS EXPRESSING A RANGE (I.E., MILD-SEVERE) OF MOTOR IMPAIRMENT CHRONICALLY AFTER STROKE WILL BE RECRUITED TO PARTICIPATE IN THIS PROJECT. MIGO'S ACCURACY AND UTILITY COST TO THE END USER WILL BE ASSESSED IN A SINGLE IN-LAB SESSION. PARTICIPANTS WILL BE OUTFITTED WITH MIGO AND PERFORM FUNCTIONAL STANDARDIZED ASSESSMENTS. AS GOLD-STANDARD COMPARISON, UPPER LIMB MOVEMENTS WILL BE COMPARED TO MOVEMENT COUNTS DERIVED FROM A VIDEO RECORDING OF THE STANDARDIZED ASSESSMENTS, WHEREAS STEP COUNTS AND STANCE/STRIDE TIME WILL BE DERIVED FROM THE ADPM SENSORS DURING A WALK TEST. RAW SENSOR DATA FROM MIGO WILL BE ANALYZED USING PROPRIETARY ALGORITHMS FOR MOVEMENT DETECTION AND COMPARED TO THE GOLD-STANDARDS TO DETERMINE ACCURACY. UTILITY COST WILL BE ASSESSED USING QUANTITATIVE SURVEY (SOCIAL ACCEPTABILITY AND EASE-OF-USE), SENSOR COST AND TIME TO DON AND DOFF EACH SENSOR TO DETERMINE THE MINIMAL NUMBER OF MIGO SENSORS AND THE OPTIMAL PLACEMENT ON THE BODY. IN A SUBSEQUENT STEP (AIM 2), SHORT TERM FEASIBILITY AND USABILITY OF THE OPTIMIZED MIGO WILL BE ESTABLISHED BY MONITORING COMMUNITY-DWELLING STROKE SURVIVORS USING MIGO OVER A 1-WEEK INTERVAL IN THE NATURAL ENVIRONMENT. ADHERENCE, OCCURRENCE OF ADVERSE EVENTS, AND SATISFACTION WITH MIGO WILL BE RECORDED. USING THE DATA FROM THE MONITORING PERIOD, PARTICIPANTS WILL BE PRESENTED WITH A 'MOVEMENT REPORT' WITH VISUAL DISPLAYS OF QUANTITATIVE AND QUALITATIVE FEEDBACK (AIM 3). THROUGH SURVEY AND QUALITATIVE INTERVIEW, WE WILL IDENTIFY THE COMPONENTS OF MIGO FEEDBACK THAT USERS FIND MOST MEANINGFUL FOR DRIVING LASTING BEHAVIOR CHANGE. THE RESULTING TECHNOLOGY WILL INTEGRATE ENGINEERING AND PATIENT-CENTERED REHABILITATION APPROACHES TO PROMOTE FULLER PARTICIPATION IN MEANINGFUL LIFE ACTIVITIES OUTSIDE CLINICAL SETTINGS IN A LESS STRUCTURED ENVIRONMENT-ONE WHERE STROKE SURVIVORS LIVE THEIR LIVES.

Posted 7/28/21, 12:00 AM