Project Grant R41HD101202

This Project Grant award from the Department of Health and Human Services National Institutes of Health National Institute of Child Health and Human Development provides $769,916 to Emergent Biotechnologies LLC for research into a novel therapy for preeclampsia. The funding supports Phase 1 of developing and characterizing a handle region peptide as an innovative treatment for preeclampsia under the Child Health and Human Development Extramural Research program (CFDA 93.865). Phase 1 work will...

This Project Grant award from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) provides $485,925 to the University of Massachusetts Boston to develop novel antioxidant compounds for treating preeclampsia, a life-threatening pregnancy complication. The primary goal is to design and synthesize cationic hydrazone antioxidants that can target mitochondria to reduce oxidative stress, improve...

This $178,000 Project Grant award from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) supports research to develop an early life phenotyping framework for very preterm infants. The research aims to create 'perinatal phenotypes' by integrating variables such as reason for preterm birth, intrapartum care, and neonatal presentation, and then determine how these phenotypes contribute to...

Novelmed Therapeutics, Inc. was awarded a $900,000 Project Grant from the National Institutes of Health's National Institute on Aging to develop a selective inhibitor of the alternative pathway of complement as a treatment for Neuromyelitis Optica Spectrum Disorder. Under the grant, Novelmed will conduct preclinical studies to evaluate its lead drug candidate NM5072, including in vitro and ex vivo assays to confirm the drug's mechanism of action and selective inhibition of the alternative...

New York University School of Medicine received a $156,080 Project Grant award effective January 1, 2026, through August 31, 2028, from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865). The research investigates the neurobiological mechanisms by which postpartum sickness impacts maternal caregiving behaviors, with particular focus on how inflammatory stress disrupts neuropeptidergic...

Novelmed Therapeutics, Inc. was awarded a $1,599,495 Project Grant from the National Heart, Lung and Blood Institute of the Department of Health and Human Services. The grant falls under the Cardiovascular Diseases Research program (CFDA 93.837), which supports heart and vascular research. Novelmed will use the funding to develop a novel disease-modifying treatment for paroxysmal nocturnal hemoglobinuria (PNH). The company's lead drug candidate selectively inhibits the alternative pathway of...

The National Institute of Child Health and Human Development (NICHD) awarded a $451,000 Project Grant (CFDA 93.865 - Child Health and Human Development Extramural Research) to The Regents of the University of California, San Francisco (UCSF) to investigate the therapeutic potential of maternal breast milk components for preterm white matter injury (WMI). The key objectives are to: 1) Perform high-throughput screening of breast milk components to identify pro-myelinating compounds, and 2) Test...

Grant Award Summary The University of Texas Southwestern Medical Center received a $456,500 Project Grant from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865), effective June 1, 2026 through May 31, 2028. The award funds research to characterize the molecular mechanisms of human cervical epithelial barrier function during pregnancy. The project delivers two primary research products: (1)...

Federal Grant Award Summary Beth Israel Deaconess Medical Center, Inc. received a Project Grant award of $164,484 from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865), effective August 1, 2025, through July 31, 2030. The award funds a research project titled "Placental NAD and Its Effect on Labor Onset," which investigates the role of nicotinamide adenine dinucleotide (NAD+)...

This $693,942 National Institutes of Health National Heart Lung and Blood Institute Project Grant funds research at Northwestern University aimed at elucidating epigenetic modifiers of regulatory T cell function following viral pneumonia. The goal is to establish causal links between DNA methyltransferase activity, the DNMT adapter UHRF1, and DNA hypermethylation signatures in regulatory T cells during aging and their impaired reparative function after severe viral pneumonia. Through three...