This $180,896 federal Project Grant award, funded by the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279), aims to use machine learning techniques to analyze integrated clinical and geosocial data to inform the design of a clinical decision support system (CDSS) to reduce the risk of stimulant therapy. The key products/services to be delivered under this 5-year award, starting July 2024, include: Retrospective analysis of electronic...
This Project Grant award of $399,414 from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), aims to discover novel small molecule therapeutics for the safe and effective treatment of opioid use disorder (OUD). The awardee, Dark Matter Therapeutics, Inc., will leverage artificial intelligence (AI) to develop a drug discovery strategy that integrates target-based and phenotype-based methodologies. This approach seeks to identify...
This $810,668 Project Grant award from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), is focused on evaluating an immunotherapeutic compound called DRHQ as a potential treatment for stimulant use disorder, specifically methamphetamine addiction. The primary objective is to demonstrate the feasibility of DRHQ, which is moving from the lead optimization stage into preclinical development. The research will be conducted by Virogenomics...
This $399,536 Project Grant was awarded by the National Institute on Drug Abuse (NIDA), a part of the National Institutes of Health (NIH), under the Drug Use and Addiction Research Programs (CFDA 93.279). The grant supports research to design, synthesize, and test non-opioid drug candidates that can help combat the national opioid crisis, with a focus on reversing the effects of synthetic opioids like fentanyl. The key goals are to: 1) Develop and characterize chemical lead compounds and control...
This $1,607,146 federal Project Grant award from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) will fund the development of community-based technology interventions to encourage drug checking, distribution of harm reduction supplies, and linkage to substance use disorder treatment services. The recipient, NDRI-USA Inc., a non-profit research organization, will use a participatory design process to create multimedia content in English...
This federal Project Grant award, totaling $346,911, was provided by the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279). The award, valid from August 15, 2024 to July 31, 2026, will support a cross-species study to identify neurocognitive, genetic, and socioenvironmental risk factors for substance use disorders (SUDs). The key objectives of the project are to: 1) determine how early life environment influences neurocognitive development...
The National Institute on Drug Abuse (NIDA) awarded a $800,000 Project Grant under the Drug Use and Addiction Research Programs (CFDA 93.279) to Tenvos Inc., a minority-owned and woman-owned technology company. The grant will support the development of a software-based medical device (SAMD) integrated into a smartphone application that can detect opioid use through voice analysis. The proposed solution aims to enable patients in outpatient opioid use disorder (OUD) treatment to remotely test for...
This $257,522 Project Grant award from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) will fund a multimodal and interdisciplinary data science training program to enhance a diverse workforce for addiction research in Mississippi. The program, led by the University of Mississippi, aims to address the lack of specialized training in artificial intelligence (AI) and machine learning (ML) methods for addiction research. It features a...
This federal Project Grant award from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) will develop novel neural network models to capture nonlinearity, enable flexible inference, and provide closed-loop control of latent brain network factors and behavior. The $1,080,885 grant, awarded on Sep 30, 2024, will support a research program to create advanced dynamical models of neural population activity that can handle missing data, operate...
The National Institute on Drug Abuse (NIDA), part of the National Institutes of Health, awarded a $399,589 Project Grant (CFDA 93.279 - Drug Use and Addiction Research Programs) to Resilient Lifescience, Inc. on September 15, 2024. The grant's objective is to develop a wearable medical device capable of detecting opioid overdose. The project is scheduled for completion by August 31, 2025. The Drug Use and Addiction Research Programs support a wide range of research activities to advance...