Project Grant R41DA045382

This Project Grant award from the National Institute of General Medical Sciences (NIGMS) under CFDA 93.859 Biomedical Research and Research Training program provides $306,860 to Mixedlcmedia LLC, a small disadvantaged business, to develop and evaluate a prototype ultra-low flow liquid chromatography platform based on their proprietary porous layer open-tubular (PLOT) and monolithic nanocolumn technologies. The goal is to create a commercialization-ready LC system that enables deep proteomic...

The National Science Foundation (NSF) Division of Electrical, Communications and Cyber Systems awarded a $399,541 Project Grant to the Trustees of Dartmouth College to develop a high-throughput, label-free, and portable sensor that can quantitatively detect multiple illicit drugs including opioids, cocaine, psychostimulants, and methadone in liquid samples such as biofluids. The project aims to create a silver or gold nanoparticle-decorated zinc oxide nanorod coated silica nanofiber matrix...

This $586,936 Project Grant award from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) supports the development of a low-cost, disposable urine test strip that can rapidly and quantitatively measure substance use disorder (SUD) medication drugs and their metabolites. The award recipient, Vitan-Biotech LLC, will create a point-of-use lateral flow assay (LFA) test strip that leverages innovative signal amplification technology to...

The National Institute of Justice (NIJ) awarded a $319,172 Project Grant under the NIJ Research, Evaluation, and Development Project Grants program (CFDA 16.560) to Research Triangle Institute (RTI International), an independent non-profit research organization. The grant funding will support evaluating the use of direct mass spectrometry technology, specifically the Luxon ion source, to improve the efficiency and capabilities of toxicology laboratories in screening for drugs related to...

This Project Grant award of $305,000 from the National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) program supports the development of a portable device for rapid, on-site detection of per- and polyfluoroalkyl substances (PFAS) in water. The award recipient, Wave Lumina Inc., will create a field-deployable sensor system that integrates surface-enhanced Raman spectroscopy and artificial intelligence-enhanced signal processing to detect PFAS at...

This Project Grant award from the National Institute on Alcohol Abuse and Alcoholism (NIAAA), funded under the Alcohol Research Programs (CFDA 93.273), provides $399,293 to Echelon Biosciences Inc. to develop a prototype rapid point-of-care phosphatidylethanol (PEth) competitive lateral flow immunoassay. PEth is considered the most reliable long-term biomarker for detecting alcohol consumption, but current testing methods are costly and have slow turnaround times. The goal of this Phase I...

This $190,662 Project Grant award from the National Institute of Justice (NIJ), under the National Institute of Justice Research, Evaluation, and Development Project Grants program (CFDA 16.560), aims to develop methods for the determination of fentanyl analogs in drug mixtures using portable Raman spectroscopy. The primary activities include: 1) Preparing a library of fentanyl spectra and mixtures using optimized surface-enhanced Raman spectroscopy (SERS) methodology; 2) Determining the...

This Project Grant award from the National Institute of Justice (CFDA 16.560 - National Institute of Justice Research, Evaluation, and Development Project Grants) provides $434,500 to 9 Delta Analytical, LLC to develop two key products: 1) An inexpensive, visually-read testing device that allows rapid identification of fentanyl and other opioids in oral fluid samples, and 2) Environmentally-friendly laboratory confirmation procedures for analyzing the same oral fluid samples. The goal is to...

This Project Grant award from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), is funding the development of a comprehensive fentanyl testing device by Taesun, LLC. The $305,369 award aims to create an integrated device that simplifies the process of fentanyl detection, making it more accessible and user-friendly for use in high-risk environments. The device will combine multiple testing steps, such as crushing, measuring, and...

This federal Project Grant award from the National Institute of Justice (CFDA 16.560 - National Institute of Justice Research, Evaluation, and Development Project Grants) provides $308,002 to Oakland University to develop an affordable, portable electrochemical sensor device for rapid, accurate detection of fentanyl and other opioids. The key objectives are to: 1) Fabricate a needle-based sensor, 2) Optimize the electrochemical signal analysis and detection for fentanyl, and 3) Test and...