Project Grant R34DA063014
Award Date
6/15/25
Completion Date
5/31/28
Dollars Obligated
$672K
Federal Agency
National Institute on Drug Abuse
Federal Grant Program
93.279
Assistance Type
Project Grant
Place of Performance
Texas, USA
Similar Awards
This $1,192,612 Project Grant award from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) will support a multidisciplinary effort to integrate HIV prevention services into clinical care settings for people with opioid use disorder (OUD). The key objectives are to: 1) conduct a systematic assessment of healthcare utilization, HIV prevention services, and medication for OUD (MOUD) using claims and emergency department data; 2) use an...
The National Institute on Drug Abuse (NIDA) awarded a $1,381,500 Project Grant (CFDA 93.279 - Drug Use and Addiction Research Programs) to the University of Nebraska Medical Center (UNMC) to explore sex differences in establishing and maintaining HIV/SIV reservoirs in the context of opioid use. The overarching goal is to delineate the role of sex factors in seeding and establishing viral reservoirs (Aim 1) and determine the location, abundance, and persistence of viral reservoirs in the...
This federal Project Grant award from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), provides $687,416 to the J. David Gladstone Institutes in San Francisco, California. The funding supports research aimed at developing therapeutic interventions to suppress the HIV reservoir in people living with both HIV and substance use disorder (SUD). Specifically, the research objectives are to: 1) Determine how inhibiting the host protein CDK9...
This federal Project Grant award, provided by the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279), aims to develop and pilot-test an intervention integrating peer navigation and family engagement to improve antiretroviral therapy (ART) adherence and opioid substitution therapy (OST) continuation among people who inject drugs in South Africa. The $873,784 award, with a project period from September 30, 2024 to August 31, 2027, will...
This Project Grant award of $234,000.00 from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) will fund research to understand the impact of opioids on HIV transcription and latency. The research will utilize a novel dual fluorescent and bioluminescent HIV virus to visualize and measure the effects of opioids like fentanyl, morphine, and methadone on HIV proviral transcription in microglia and astrocytes. The goal is to identify key...
This federal Project Grant award of $1,932,699.00, awarded by the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279), supports research to evaluate the effectiveness and implementation of a peer-delivered behavioral activation and problem-solving intervention called "Peer Activate-LAI" for improving adherence to long-acting injectable pre-exposure prophylaxis (PrEP) and antiretroviral therapy (ART) among a predominantly Black,...
This Project Grant award in the amount of $983,672.00 was issued by the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279). The award will fund research to characterize the in-situ spatial interactions between HIV-infected cells and immune cells in the central nervous system (CNS) of people living with HIV, with a focus on understanding the impact of methamphetamine use on neuroinflammation. The research will leverage a unique cohort of brain...
This Project Grant award from the National Institute on Drug Abuse (NIDA) under CFDA 93.279 - Drug Use and Addiction Research Programs is for a 2-year study titled "SILOS: Structural Inequities Across Layers of Social-Context as Drivers of HIV and Substance Use." The $2,332,704 award will fund innovative observational research across 5 U.S. cities to better understand how social contexts and inequities drive disparities in HIV and substance use among racial, ethnic, and sexual/gender...
This Project Grant, award ID R61DA061371, is funded by the National Institute on Drug Abuse (NIDA) under the federal Drug Use and Addiction Research Programs (CFDA 93.279). The $1,826,522 award will support the development and implementation of a digital, decision-support toolkit to address intimate partner violence (IPV), posttraumatic stress disorder (PTSD), and opioid use disorder (OUD) in opioid treatment programs. The project includes three aims: 1) conducting stakeholder interviews to...
This federal Project Grant award for $263,119 from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) is focused on developing NLRP3 inhibitors to address HIV-associated neuroinflammation in cocaine use. The key objectives are to computationally design, synthesize, and screen novel analogues of a lead compound, AMS-17, to improve its biological activity and maintain low toxicity. The project involves in vitro and in vivo screening of...