This Project Grant award of $1,717,104 from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), will fund a 3-year collaborative effort to adapt, produce, and pilot test a written "Youth Overdose Prevention Toolkit" for use in pediatric healthcare settings. The toolkit will provide clinicians with practical, evidence-based guidance on delivering interventions such as naloxone distribution, take-home drug testing, harm reduction...
This federal Project Grant award, provided by the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279), aims to develop and evaluate the efficacy of a universal overdose prevention intervention to be delivered in primary care settings for youth ages 13 to 26. The $2,467,574 award will fund a two-phase project. In the first R61 phase, the grantee, Boston Medical Center Corporation, will collaborate with a youth advisory board to develop the...
This $197,748 Project Grant award from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), will support research to develop and pilot an enhanced low-dose buprenorphine initiation (LDI) program to improve treatment outcomes for individuals with opioid use disorder (OUD), especially those using fentanyl. The key objectives of this 4-year project are to: 1) identify barriers to successful LDI completion through qualitative interviews, 2)...
This federal Project Grant award of $431,750, issued by the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279), will support research to identify individual and clinical care factors associated with adolescent drug overdose risk. The key objectives are to: 1) estimate the prevalence of nonfatal drug overdoses in adolescents aged 12-18 and identify high-risk demographic and clinical subgroups, 2) examine behavioral health treatment received...
This $4,801,857 federal Project Grant award, funded by the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279), supports research to compare the effects of different medications for opioid use disorder (MOUD) on neuroinflammation and neurocognition in people living with HIV (PLWH). The goal is to evaluate whether opioid antagonist MOUD (e.g., XR-naltrexone) have anti-inflammatory and neuroprotective effects compared to opioid agonist MOUD...
This federal Project Grant award of $459,045, provided by the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279), will fund a study to modify the Opioid Use Disorder (OUD) Cascade of Care model to better reflect the current landscape of OUD treatment delivery. The RAND Corporation, a nonprofit global policy think tank, is the prime awardee on this 2-year grant with a period of performance from September 30, 2024 to September 29, 2026. The key...
This $1,607,146 federal Project Grant award from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) will fund the development of community-based technology interventions to encourage drug checking, distribution of harm reduction supplies, and linkage to substance use disorder treatment services. The recipient, NDRI-USA Inc., a non-profit research organization, will use a participatory design process to create multimedia content in English...
The National Institute on Drug Abuse awarded Boston Medical Center Corporation (BMC) a $994,004 Project Grant under the Drug Use and Addiction Research Programs (CFDA 93.279) to conduct the Youth Empowerment Study (YES). The study aims to: Explore perceptions of overdose risk, the drug supply, and safety precautions among adolescents (ages 13-17) and young adults (ages 18-25) through focus groups and a photovoice component. Investigate perspectives of families, youth providers, pharmacists,...
This National Institute on Drug Abuse (NIDA) Project Grant award under CFDA 93.279 "Drug Use and Addiction Research Programs" is for $195,156.00 over the period of Jul 1, 2024 to Jun 30, 2029. The award will fund the development and evaluation of a novel family-based digital intervention called "FamilyBond" (FAMB) to prevent substance misuse among urban Black adolescents aged 14-17 in primary care settings. The key objectives are to: 1) develop and assess the usability of...
This $2,881,950 Project Grant award from the National Institute on Drug Abuse (CFDA 93.279 - Drug Use and Addiction Research Programs) will fund the "Functional Connectivity Mechanisms of Opioid Abstinence" research project at Yale University from July 1, 2024 to April 30, 2029. The project aims to investigate neurological mechanisms underlying opioid use disorder (OUD) and treatment, with a focus on factors influencing relapse and treatment adherence for patients receiving medications...