Planning grant for a multi-site trial to examine the effectiveness of recovery community centers serving black communities to support persons using medications for opioid use disorder

Active Project Grant Awarded Last action

Award ID
R34DA057604
Recipient
Awarding agency
Obligated
$2,217,344

Award facts

Assistance listing
93.279 Drug Use and Addiction Research Programs
Completion date 81% complete
Originally
Place of performance
Boston, MA 02114, USA

Award details come from USAspending.gov.

Description

As the agency reported it.

Abstract
To address the ongoing opioid epidemic, the U.S. Department of health and human services (HHS) seeks to improve access to treatment and recovery services. Currently, the gold-standard treatment for opioid use disorder (OUD) is long-term treatment using FDA-approved medications (mouds). Early discontinuation of moud use represents a critical barrier to the effectiveness of mouds, as more than half of persons who start moud use discontinue IT early. Approaches are needed that support persons initiating moud treatment to stay engaged in medication assisted recovery over the longer term. Recovery community centers (rccs) are emerging as an important third component of recovery-oriented systems of care that, until recently, were comprised solely of professional treatment and mutual-help organizations. These centers provide a welcoming recovery-oriented environment for persons using mouds that provide a range of recovery-oriented, peer- delivered services over the long-term. Despite recent rapid large-scale investment in their growth, empirical data on the functioning and outcomes of rccs are extremely limited. Critically needed is research that can speak to the effectiveness of rccs. To address this need, and in line with RFA-DA-22-034's use of the R34 planning grant mechanism, we propose to conduct three preparatory studies that can inform the design and logistics of a planned subsequent rigorous R01-level trial. Our proposal builds on two key strengths: (1) our existing and growing nida-funded infrastructure to advance the science on rccs (R24 DA051988; m-PIS: hoeppner & kelly), which allowed US to build relationships with rccs nationwide and gain insight into consensus around appropriate outcome measures, and (2) the existing relationships of the rccs participating in this project with moud-providing clinics near them. Because the covid-19 pandemic is widening health disparity gaps, including widening disparities in OUD care, our focus is on rccs serving black communities. Using a community-based participatory research approach, our aims are to provide insight into key components of the planned subsequent rigorous R01-level trial using three distinct lines of inquiry. Aim 1 is to conduct a (small, multi-site) naturalistic longitudinal study of moud clinic patients to provide insight into the appropriateness of study procedures, and to receive feedback on randomization procedures. Aim 2 is to conduct a (small, multi-site) pilot randomized clinical trial (RCT) comparing two randomized groups of persons engaged in moud clinical care: those who receive linkage to their nearby RCC VS. Those who do not. Aim 3 widens the lens beyond the rccs participating in aims 1 and 2. Directors and front desk staff of moud- providing clinics near rccs serving black communities will be surveyed and interviewed to identify barriers to incorporating a potential RCC linkage into moud clinics' standard clinical care models. Together, these three studies will guide the design of a large-scale subsequent R01 level RCT.

Transactions

Action Obligated Date
Amendment $0
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Amendment $235,860
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Amendment Research supplement to promote diversity within the context of research involving recovery community centers $0
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Amendment Research supplement to promote diversity within the context of research involving recovery community centers $130,416
Amendment $130,416
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Amendment Research supplement to promote diversity within the context of research involving recovery community centers $0
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Amendment Research supplement to promote diversity within the context of research involving recovery community centers $0
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Amendment $742,396
Original award $742,396
Show all 29

Subawards

Subrecipient Amount Awarded
Lets Talk Safety Inc. This is a research training fellowship. Dr. Felecia Pullen will receive training and mentoring in conducting research. This will include: In year 1, Dr.… $113,666
Northern Ohio Recovery Association In year 1, Mrs. Anita Bradley, Ms. Cathy Davis (Site Co-PIs) and paid RCC staff will complete IRB-required trainings in the ethical conduct of research provided… $78,600
Detroit Recovery Project In year 1, Mr. Andre Johnson, Ms. Angela Burton (Site Co-PIs) and paid RCC staff will complete IRB-required trainings in the ethical conduct of research… $74,580

Quick answers

Who received award R34DA057604?

R34DA057604 was awarded to The General Hospital Corporation by National Institute on Drug Abuse (National Institutes of Health) on September 30, 2022.

How much is award R34DA057604 worth?

$2,217,344 has been obligated on R34DA057604.

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