Fair DOS: findable, accessible, interoperable, reusable development of open simulation

Active Project Grant Awarded Last action

Award ID
R25DK130611
Recipient
Awarding agency
Obligated
$910,794

Award facts

Completion date 85% complete
Place of performance
La Jolla, CA 92093, USA

Award details come from USAspending.gov.

Description

Abstract
Fair DOS (findable, accessible, interoperable, reusable: development of simulations) is a 5-year research education program in the modeling and simulation of digestive and renal neurobiology. IT is developed by a team of award-winning faculty of educators and researchers who, among other things, is behind the fair mapping and knowledge management infrastructure for the sparc effort. The main thrust of fair DOS is to educate the next generation of researchers and clinicians in the neural regulation of digestive and renal epithelia through taught modules and supervised modeling projects that make use of sparc datasets, maps, and models. The fair DOS faculty will leverage teaching structures at case western reserve university to recruit students. Overall, fair DOS aims to provide about 35/45 hours of training to over 75 students over the proposed five-year project, with each student research project producing one publication in the physiome journal – launched by the international union of physiological sciences. The sparc portal will provide findability to these student- generated open-access models and associated data via its search and flatmaps functions, as well as accessible interactivity via the O2S2PARC simulation platform. Overall, the fair DOS effort will provide a unique educational, mentored experience that will also generate a sparc ecosystem of interoperating models that coherently study the neurobiology of digestive and renal epithelial transport. From a didactic "systems" perspective, this ecosystem of models will be organized to follow the teaching narrative of the british medical association award-winning "medical physiology 3RD ED." textbook, supplemented with recent literature, setting the stage to further leverage sparc resources for education in the future.

Transactions

Action Obligated Date
Amendment $129,600
Amendment $129,600
Amendment $129,600
Amendment $130,597
Amendment $130,597
Amendment $130,400
Original award $130,400

Subawards

Subrecipient Amount Awarded
Case Western Reserve University Mod: 54,000.00 11/7/2025 Mod: 54,000.00 05/20/2025 Mod: 54,000.00 09/07/2023 Sub: $54,000.00 01/31/2023 Case Western Reserve University SOW FAIR DOs… $216,000
The University Of Auckland Mod: $32,400.00 09/13/2024 Mod: $32,400.00 10/16/2023 Sub: $32,400.00 01/19/2023 SOW - UoA UoA will provide bond graph templates for model development and a… $97,200
Whitby Et AL, LLC Mod: 45,360.00 1/12/2026 Mod: $12,960.00 10/16/2024 Mod: $12,960.00 09/11/2023 Sub: $12,960.00 12/15/2022 FAIR Dos aims to build models of cellular transport as… $84,240

Quick answers

Who received award R25DK130611?

R25DK130611 was awarded to University Of California, San Diego by National Institute of Diabetes and Digestive and Kidney Diseases (National Institutes of Health) on September 20, 2022.

How much is award R25DK130611 worth?

$910,794 has been obligated on R25DK130611.

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