Project Grant R21HD122088
- The National Institute of Child Health and Human Development awarded Children's Research Institute $794,699 on June 18, 2026, under the Child Health and Human Development Extramural Research program (CFDA 93.HDR) to conduct research on maternal depression and antidepressant effects on fetal brain structure and function (FABMOMS). The research evaluates the separate and interactive effects of in utero exposure to serotonin reuptake inhibitors and maternal major depressive disorder on fetal and...
- Federal Grant Award Summary The Children's Research Institute received a $500,500 Project Grant from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865), effective June 1, 2025, through May 31, 2027. The award funds the development of quantitative electroencephalogram (EEG) biomarkers for Smith-Magenis Syndrome (SMS), a rare neurodevelopmental disorder caused by deletion or mutation of the...
- The National Institute of Child Health and Human Development awarded The Johns Hopkins University $168,988 on August 24, 2026, under the Child Health and Human Development Extramural Research (CFDA 93.865) program to develop and pilot an illness-specific safe sleep intervention for infants delivered via text message after pediatric emergency department visits. Dr. Howard, under mentorship of Drs. Rachel Moon and Leticia Ryan, will conduct research addressing sudden unexpected infant death...
- The National Heart, Lung, and Blood Institute awarded Children's Research Institute $1,818,088 on July 15, 2026, under the Cardiovascular Diseases Research program (CFDA 93.837) to investigate how postnatal hypoxemia—reduced blood oxygen levels present in cyanotic congenital heart disease—impacts cardiac maturation and surgical recovery outcomes in pediatric patients. The project will examine the interaction between hypoxemia, myocardial immaturity, and postoperative complications through...
- The National Institute of Child Health and Human Development awarded Seattle Children's Hospital $380,774 on June 1, 2026, to develop and pilot a parent-facing tool designed to improve neonatal clinical trial recruitment and readiness among NICU parents. The project develops a web-based, mobile-accessible tool using multimedia and interactive features to prepare parents in neonatal intensive care units for discussions with clinical researchers about research enrollment. Development follows...
- The National Institute of Child Health and Human Development awarded New York University $466,125 on September 1, 2026, under the Child Health and Human Development Extramural Research Program (CFDA 93.865) to validate scalable, gaze-based executive function assessment tasks for infants and toddlers ages 6 to 30 months. The research will develop and test two webcam-compatible, eye-tracking paradigms designed to measure inhibitory control, working memory, and cognitive flexibility in brief...
- The National Institute of Child Health and Human Development awarded The Children's Hospital of Philadelphia $795,088 on June 15, 2026, under the Child Health and Human Development Extramural Research program (CFDA 93.865) to conduct a cluster randomized controlled trial evaluating doula support and healthcare navigation for mothers of preterm infants in neonatal intensive care units. The study, titled Postpartum Care in the NICU (PELICAN), addresses maternal postpartum mortality risk among...
- The National Institute of Child Health and Human Development awarded the Rehabilitation Institute of Chicago, doing business as Shirley Ryan AbilityLab, $720,463 on July 3, 2026, under the Child Health and Human Development Extramural Research program (CFDA 93.865) to develop a fully automated wearable sensor toolkit for early detection and surveillance of infant motor deficits. The toolkit will detect motor deficits in infants within the first few months of life during free-living activities in...
- Federal Project Grant Award Summary The National Institute of Child Health and Human Development (NICHD) awarded $434,500 to the Research Institute at Nationwide Children's Hospital under the Child Health and Human Development Extramural Research program (CFDA 93.865) for the period August 1, 2025, through July 31, 2027. The funded project, "NEOGX-III: Interpretable Machine Learning with Integrated Analysis of Maternal & Infant Electronic Medical Records for Unbiased Prediction of...
- The National Institute of Child Health and Human Development awarded the University of Illinois $498,000 on February 1, 2026, under the Child Health and Human Development Extramural Research Projects program (CFDA 93.865) to investigate neural markers of developmental delays in premature and full-term infants. The recipient will chart brain development using electroencephalography (EEG) during well-baby visits at 4, 9, and 12 months at a primary care clinic and at a 24-month follow-up lab visit,...
The National Institute of Child Health and Human Development awarded Children's Research Institute $500,500 on September 1, 2026, under the Child Health and Human Development Extramural Research program (CFDA 93.HDR) to conduct a prospective observational study integrating bedside sleep monitoring tools for preterm infants during the neonatal intensive care unit (NICU) stay. The research addresses sleep-cycle maturation in preterm infants born during the extrauterine third trimester. Sleep disturbances in the NICU environment may serve as a modifiable risk factor for cognitive-behavioral deficits in prematurely born children. The study will use quantitative analysis of heart rate and respiratory rate variability derived from electrocardiogram and pulse oximetry—tools already routinely acquired at the NICU bedside—to identify sleep states (awake, active sleep, quiet sleep, and transitional sleep) in real time. The investigators will enroll 60 preterm infants and compare the agreement between bedside-accessible physiologic measures and benchmark sleep assessment tools (video-electroencephalography and polysomnography) to develop a pragmatic, non-invasive classification model. Characterizing longitudinal sleep-cycle maturation may provide early biomarkers of brain maturation with prognostic value for cognitive outcomes in childhood. The performance period runs from September 1, 2026, through August 31, 2028, with work performed in Washington, DC. Children's Research Institute, a tax-exempt pediatric research organization and research subsidiary of Children's National Medical Center, serves as the recipient.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $500.5k | 8/6/26 |