Project Grant R21HD116006
Award Date
4/17/25
Completion Date
3/31/27
Dollars Obligated
$270K
Federal Agency
National Institute of Child Health and Human Development
Federal Grant Program
93.865
Assistance Type
Project Grant
Place of Performance
Wisconsin, USA
Similar Awards
This federal Project Grant award from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), provides $135,864 to the Whitehead Institute for Biomedical Research in Cambridge, MA to develop a novel experimental vertebrate regeneration system using the Danionella cerebrum fish species. The key objectives of this 2-year project are to: 1) Generate a comprehensive single-cell RNA sequencing...
This federal Project Grant award for $103,226 from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program will support research aimed at identifying the immune regulation pathways necessary for spinal cord regeneration in adult zebrafish. The primary objectives are to: 1) Define the genes upstream of wound healing that are necessary for re-establishing immune privilege in the...
The National Institute of Child Health and Human Development (NICHD) awarded a $330,000 Project Grant under CFDA 93.865, the Child Health and Human Development Extramural Research program, to the Rehabilitation Institute of Chicago (doing business as Shirley Ryan AbilityLab), a nonprofit hospital and research institute. The grant, titled "Engaging Reticulospinal Inputs to Improve Walking," aims to examine the contribution of the reticulospinal tract to lower limb muscle activity during...
This federal Project Grant award from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), provides $487,559 to Yale University to study the molecular biophysics and systems morphogenesis involved in early spinal column development using zebrafish as a model. The key focus of the research is to quantify the dynamics of integrin heterodimer activity, which serves as the primary cell surface...
This federal Project Grant award from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), provides $169,000.00 to President and Fellows of Harvard College to build a single-cell reference atlas of axolotl embryogenesis. The goal is to identify the origin and nature of stem cells in axolotl embryos, which could inform future studies on limb regeneration. This work will map the transcriptional...
This Project Grant award from the National Institute of Child Health and Human Development (CFDA 93.865 - Child Health and Human Development Extramural Research) provides $195,896 to the University of Oregon to support research on the role of sonic hedgehog signaling in skeletal patterning during zebrafish fin regeneration. The project aims to identify sonic hedgehog target genes and how they promote interactions between sonic hedgehog-expressing basal epidermal cells and progenitor...
The National Institute of Child Health and Human Development (NICHD) awarded a $350,604 Project Grant (CFDA 93.865 - Child Health and Human Development Extramural Research) to The Trustees of the University of Pennsylvania, doing business as Clinical Practices of the University of Pennsylvania, on August 10, 2024. The grant supports a research project titled "Molecular Basis for BMP Receptor Specialization and Trafficking" that aims to determine the specialized roles of different...
This $1,344,373 Project Grant award from the National Institutes of Health (NIH) under the Trans-NIH Research Support program (CFDA 93.310) supports research to investigate cardiac regeneration in human cells and zebrafish models. The primary objectives are to: (I) assess the dynamic gene regulatory networks involved in zebrafish heart regeneration using single-cell ATAC-seq, (II) interrogate the reactivation of developmental gene programs in human cardiac organoids after injury using multiomics...
The National Institute of Child Health and Human Development (NICHD) awarded a $562,740 Project Grant (CFDA 93.865 - Child Health and Human Development Extramural Research) to Baylor College of Medicine to develop less invasive, novel intervention strategies for the endogenous in utero repair of spina bifida. The project aims to devise biomimetic therapeutic strategies that can induce a regenerative cascade at the site of spina bifida lesions and activate the cellular and molecular processes...
The National Institute of Child Health and Human Development (NICHD) awarded a $104,838 Project Grant (CFDA 93.865 - Child Health and Human Development Extramural Research) to Duke University to conduct research on the BMP signaling pathway and its role in embryonic development. The research program will employ cutting-edge quantitative live imaging techniques, mathematical modeling, and tools for studying BMP signaling in diverse insect species to shed light on how cells perceive and respond to...