Project Grant R21HD114233

Award Date 9/1/24
Completion Date 8/31/26
Dollars Obligated $194K
Federal Grant Program
93.865
Assistance Type
Project Grant
Place of Performance
Riverside, CA 92521, USA
Similar Awards
The federal Project Grant award R03HD114194, in the amount of $330,000.00, was awarded by the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865). The grant will fund a research project conducted by Trustees of Boston University to characterize functional and anatomical patterns of brain connectivity in children with unilateral cerebral palsy (UCP) and relate these patterns to impairments in...
This Project Grant award from the National Institute of Child Health and Human Development (CFDA 93.865 - Child Health and Human Development Extramural Research) aims to develop advanced in vivo magnetic resonance imaging (MRI) technologies for studying infant brain development. The $537,730 award to The Leland Stanford Junior University will focus on three key objectives: 1) Developing acquisition and reconstruction strategies for 600mm whole-brain multi-parametric quantitative MRI (qMRI) to...
The National Institute of Child Health and Human Development (NICHD) awarded a $218,265 Project Grant (CFDA 93.865 - Child Health and Human Development Extramural Research) to the University of Wisconsin - Madison to develop quantitative ultrasound (QUS) imaging technology for detecting cell death in the brains of human neonates. The key objectives are to first optimize QUS data acquisition and analysis in typically developing neonatal brains to establish normative data for selected brain...
This Project Grant award from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), will support research to investigate descending motor pathways and their involvement in post-stroke hemiparesis. The primary objectives are to: Use multi-echo fMRI to evaluate neural activity patterns in the brain, brainstem, and spinal cord during unilateral hand-grasping tasks with the paretic versus...
This Project Grant award from the National Institute of Child Health and Human Development (CFDA 93.865 - Child Health and Human Development Extramural Research) will develop a new approach for secondary fetal screening using 0.55T MRI technology. The $707,218 award to Children's Hospital Los Angeles aims to assess the potential of lower-field 0.55T MRI to serve as an alternative screening modality for high-risk pregnancies with poor acoustic windows that compromise the diagnostic utility of...
This Project Grant award from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) provides $566,323 to Case Western Reserve University to develop advanced MRI fingerprinting techniques for comprehensive imaging of infant and young child brain development. The key objectives are to: 1) Create a motion-robust MRI fingerprinting scan to quantify multiple tissue properties in non-sedated infants...
This federal Project Grant award from the National Institute of Child Health and Human Development (CFDA 93.865: Child Health and Human Development Extramural Research) provides $213,750 to Children's Hospital Los Angeles to conduct a prospective observational study on the accuracy and feasibility of point-of-care, low-field magnetic resonance imaging (POC LF-MRI) for evaluating pediatric traumatic brain injuries (TBI) in emergency and critical care settings. The study aims to (1) determine...
This $423,151 federal Project Grant award from the National Science Foundation's Engineering program (CFDA 47.041) aims to develop a new functional brain imaging technology that can provide high-resolution, deep-brain neural activity mapping. The project, led by Duke University, focuses on three key technical thrusts: 1) improving the temporal resolution of super-resolution ultrasound imaging using deep learning, 2) developing an ultrafast ultrasound system for efficient image reconstruction,...
This $2,278,167 Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) supports the development of non-invasive transcranial volumetric super-resolution imaging, targeted contrast agents, and image-guided focused ultrasound surgery. The University of North Carolina at Chapel Hill and the California Institute of Technology will...
This $312,039 Project Grant award from the National Science Foundation's Engineering program (CFDA 47.041) supports research by the University of California, Irvine to develop conformable, expandable neural interface devices. The goal is to use these bioelectronic devices to monitor brain activity in immature rodents as they perform naturalistic behaviors, with the aim of identifying neurophysiological signatures of emerging cognitive processes. The research seeks to provide insights into how...

The Project Grant award R21HD114233 for $193,953 from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), will fund research to develop and apply a novel ultrasonic brain imaging technology (functional ultrasound imaging, or FUSI) to study motor activity in behaving infants.

The key objectives are to: 1) Assess the functional organization of the infant motor system using FUSI while infants perform reaching tasks, and 2) Develop tools to decode motor activity in the infant brain from FUSI data, with the eventual goal of enabling non-invasive brain-machine interface systems for motor rehabilitation in young populations. The research will be conducted by the Regents of the University of California at Riverside, with a sub-award to Casa Colina Hospital and Centers for Healthcare to support the project. This work aims to provide neuroscience with high-resolution neuroimaging capabilities for monitoring brain activity in awake, behaving infants, while laying the foundation for innovative ultrasound-based technologies to assist with motor rehabilitation.

Generated 6/17/25, 5:54 AM