This Project Grant award of $864,040 from the National Eye Institute (CFDA 93.867 Vision Research) will fund research to develop and test an intraocular projection system that can be implanted in the eye to restore vision for patients with severe corneal injury or damage. The award supports three key objectives: 1) implanting 25 dummy intraocular lenticule implants of varying weights in rabbits to identify weight limits before instability, 2) implanting 25 semi-active lenticule implants in...
This Project Grant award of $162,486 from the National Eye Institute (NEI), under the Vision Research federal grant program (CFDA 93.867), aims to study the stimulation of long-range cortical projections involved in visual-spatial behavior in non-human primates using a novel multimodal optoelectronic device. The key objectives of the project are to: 1) develop a multimodal optoelectronic device with microLED and transparent microelectrodes to enable colocalized optogenetic stimulation and...
This $673,747 Project Grant award from the National Eye Institute (CFDA 93.867 Vision Research) supports a research initiative at New York University School of Medicine to develop a novel visible-to-near-infrared optical coherence tomography (OCT) system for high-resolution retinal imaging. The project aims to quantify retinal biomarkers like macular pigments and retinal pigment epithelium melanosomes that are important indicators of age-related macular degeneration (AMD) progression, with the...
The National Eye Institute (NEI) awarded a $256,296 Project Grant (CFDA 93.867 - Vision Research) to The General Hospital Corporation (Massachusetts General Hospital) to develop new "Auto-Sensing, Instantaneous Adaptive Ranging Optical Coherence Tomography (OCTA)" technology. This technology aims to expand the imaging depth range of OCTA systems, enabling improved visualization of the critical peripheral retinal microvasculature. The project will leverage advances in integrated...
This federal Project Grant award of $305,000 from the National Eye Institute (CFDA 93.867 - Vision Research) aims to develop and validate a novel adaptive optics optical coherence tomography (AO-OCT) system tailored for high-resolution, wide-field retinal imaging in small animal models, specifically mice. The key products and services to be delivered under this 1-year project include: Designing and fabricating an integrated AO-OCT system with a 150-degree field of view and 2-micron resolution,...
The federal Project Grant award of $427,625 was provided by the National Eye Institute (NEI) under the Vision Research program (CFDA 93.867). The award aims to investigate the interplay between debris/dying cell clearance by specific phagocytes in the retina and the possibility of improving retinal tissue healing in oxygen-induced retinopathy (OIR). The research will use chimeric efferocytosis (CHEF) receptors to improve the efferocytic capacity of retinal phagocytes and evaluate the impact on...
This federal Project Grant award of $606,025 from the National Eye Institute (CFDA 93.867 Vision Research program) supports research by William Marsh Rice University to develop a visual prosthesis that can restore pattern vision for blind individuals by interfacing with the lateral geniculate nucleus (LGN) of the brain. The key objectives are to establish the feasibility and acquire the knowledge needed to build a lasting LGN-based visual prosthesis with unprecedented visual field coverage....
This Project Grant award for $687,692 from the National Eye Institute (CFDA 93.867 - Vision Research) aims to develop an open-source, extended-reality platform that can make basic vision science assessments and interventions accessible to people living with visual impairments. The project, led by Northeastern University, seeks to leverage vision science insights, software development, and extended-reality headsets to create a platform that can bring lab-based vision evaluations and therapies...
This Project Grant awarded by the National Science Foundation (CFDA 47.084 - NSF Technology, Innovation, and Partnerships) provides $304,998 to Glaive Medical Optics Inc. to develop a novel implantable intraocular lens that can shift the phase of visible light to mitigate vision loss due to age-related macular degeneration. The project aims to create an energy-efficient, small-form factor optical phased array that can electronically adjust visible light frequencies to focus on viable regions...
This Project Grant award of $482,312 from the National Eye Institute (CFDA 93.867 Vision Research program) supports research to develop a dynamic spatiotemporal normalization framework for understanding human visual perception. The research aims to investigate how visual perception is shaped by the temporal context of visual input, as well as the interaction between temporal attention and temporal normalization processes. The 5-year project, awarded to the Trustees of Boston University and...
This Project Grant award from the National Eye Institute (CFDA 93.867 Vision Research) provides $1,765,704 to Trustees of Boston University to develop an injectable optoacoustic retina prosthesis for high-precision retinal stimulation. The project aims to create a minimally invasive, soft, and biocompatible optoacoustic material that can be injected into targeted areas of the retina and stimulate it with micrometer-scale spatial resolution. The research team, led by Prof. Chen Yang, will develop the injectable material, demonstrate high-precision retinal stimulation, and evaluate the safety and efficacy of the technology in rodent models. A sub-award of $TBD to Fondation Voir Et Entendre in France will support the rodent model testing and validation of the injectable prosthesis. This effort is expected to generate a conceptually new prosthesis design offering high-precision, parallel, and genetics-free optoacoustic stimulation with translational potential for treating vision loss.