The National Eye Institute (NEI) awarded a Project Grant (CFDA 93.867 Vision Research) worth $210,534 to Legacy Emanuel Hospital & Health Center in Portland, Oregon. The grant, which runs from September 1, 2024 to August 31, 2026, will fund research to investigate the cellular, molecular, and structural alterations in the optic nerve head associated with the development and progression of juvenile myopia using a tree shrew model. Key objectives of the project include assessing changes in axonal health, myelin, and immune cell infiltration in the optic nerve head, and correlating these micro-level alterations with tissue-level changes observed through optical coherence tomography (OCT) imaging. The University of Alabama at Birmingham received a $YND4PLMC9AN7 sub-award to conduct the experimental procedures to induce myopia in tree shrews, perform longitudinal in vivo OCT imaging and biometric measurements, and analyze the data. The research aims to advance the understanding of the pathogenesis of myopia and open new avenues for developing novel treatment strategies.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $210.5k | 8/28/24 |
Grant Number | Description | Subgrantee | Prime Award | Dollars Obligated (Click to sort descending) | Updated At (Click to sort ascending) |
|---|---|---|---|---|---|
PC202401S | University Of Alabama At Birmingham | Project Grant R21EY036560 | $108.9k | 9/5/24 |