Characterizing the prevalence and nature of facial recognition deficits in non-proliferative diabetic retinopathy
Active Project Grant Awarded Last action
- Award ID
- R21EY034326
- Recipient
-
University Of Oklahoma UEI EVTSTTLCEWS5
- Awarding agency
-
National Eye Institute
National Institutes of Health, Department of Health and Human Services
- Obligated
- $782,475
Award facts
- Assistance listing
- 93.867 Vision Research
- Completion date 86% complete
- Originally
- Place of performance
- Oklahoma City, OK, USA
Award details come from USAspending.gov.
Description
- Abstract
- Facial perception and memory are visual abilities that are driven by an interplay between low-level visual and higher-level cognitive functioning. Decits in facial perception and memory are associated with diminished quality of life and a range of social challenges, and IT has been suggested that this functional decit may be an early marker for the later onset of structural abnormalities in a variety of conditions. One of these conditions-one that has received scant attention-is diabetic retinopathy. In a recent systematic review, difculty in perceiving faces was noted as one of the greatest subjective restrictions on visual functioning. Diabetic retinopathy affects approx- imately one-third of individuals with diabetes world-wide. The vision loss associated with diabetic retinopathy is preventable, given early identication, medical intervention and monitoring, and behavioral interventions. Diabetic retinopathy can be generally separated into two classes. The RST is non-proliferative diabetic retinopathy, which is characterized by micro-aneurysms, intraretinal hemorrhages, venous beading or intra-retinal microvascular AB- normalities. The second is proliferative diabetic retinopathy, which is characterized by retinal neovascularization. In cases of macular edema, there is a thickening of the macula which can result in the loss of central vision. Decits in face processing have been studied more frequently in two pathologies that affect the macula: age- related macular degeneration (AMD) and glaucomatous macular damage. Patients with AMD regularly identify facial processing as tasks with which they experience signicant difculty. In the literature on AMD, decits in facial processing have been identied as signicant components of quality of life. The magnitude of the decits in facial processing in AMD are such that they are second only to decits in reading in subjective complaints. Finally, IT has been noted that decits in facial processsing are among the RST subjectively-reported symptoms of AMD, often occurring before the detection of structural abnormalities. With respect to decits in facial percep- tion and memory in glaucomatous macular damage, there is evidence that signicant impairments exist despite patients having good central visual acuity. In addition, the amount of the diffuse macular damage is signicantly related to impairments in contrast sensitivity and measures of facial recognition and identication. IT has been suggested that other related visual pathologies-including diabetic retinopathy-should show similar patterns of performance decits. However, very little work on this issue has been done in the case of diabetic retinopa- THY. The work proposed here represents an important RST step in addressing this need. The accomplishment of this work will result in the RST quantication of the prevalence and severity of decits in facial processing in diabetic retinopathy, the RST analytic empirical treatment of the pathology-related differences in processing feat- ural and congural information, and the RST theoretical treatment of those differences. The novel application of two meta-theories using a new experimental design, along with a modeling approach capable of relating those meta-theories has the potential to be transformative in this domain.
Transactions
| Action | Obligated | Date |
|---|---|---|
| Amendment | $0 | |
| Amendment | $0 | |
| Amendment | $0 | |
| Amendment | $206,229 | |
| Amendment | $0 | |
| Amendment | $0 | |
| Amendment | $192,082 | |
| Amendment | $192,082 | |
| Original award | $192,082 |
Subawards
| Subrecipient | Amount | Awarded |
|---|---|---|
| Retina Consultants Of Oklahoma PLLC | $129,250 | |
| Trustees Of Indiana University | $44,734 |
Quick answers
Who received award R21EY034326?
R21EY034326 was awarded to University Of Oklahoma by National Eye Institute (National Institutes of Health) on June 1, 2023.
How much is award R21EY034326 worth?
$782,475 has been obligated on R21EY034326.
On GovTribe
See this award's full record
- Every transaction and subaward
- The recipient's other awards and teaming partners
- Similar grant awards
- Ask GovTribe AI about this award