This $1,193,500 Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) supports research to investigate the mechanisms by which transcranial alternating current stimulation (tACS) and transcranial direct current stimulation (tDCS) modulate cerebral microvascular function and its influence on neuronal activity. The Lovelace Biomedical Research Institute will conduct in-vivo studies using awake multiphoton microscopy to assess changes in microvascular tone,...
This federal Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under CFDA 93.846 (Arthritis, Musculoskeletal and Skin Diseases Research) provides $488,782 to The University of Kentucky Research Foundation to conduct a mechanistic assessment of neuromuscular electrical stimulation (NMES) to address localized neuromuscular disruption after anterior cruciate ligament (ACL) injury. The overarching goal is to establish the causative roles of...
This $216,210 Project Grant awarded by the National Institute on Aging (CFDA 93.866 - Aging Research) supports research on the potential of transcranial direct current stimulation (tDCS) as a therapeutic intervention to improve neurovascular coupling and cognitive function in stroke survivors with post-stroke cognitive impairment (PSCI). The project aims to comprehensively evaluate neurovascular coupling responses in stroke survivors with and without cognitive impairment, and conduct a...
The National Science Foundation (NSF) is providing a $170,617 Project Grant under its Engineering program (CFDA 47.041) to the University of Illinois to advance the scientific study of brain functional changes after a stroke and pioneer a tailored rehabilitation strategy that fits each individual's needs. The 5-year project aims to combine different imaging methods to guide electrical brain stimulation that improves the recovery of movement for stroke patients, potentially benefiting over half a...
This Project Grant award from the National Institute of Child Health and Human Development (NICHD) under CFDA 93.865 - Child Health and Human Development Extramural Research program provides $634,238 to the University of Texas at Austin (UT Austin) to demonstrate the feasibility of a real-time EEG-informed transcranial magnetic stimulation (TMS) system for enhancing post-stroke hand rehabilitation. The project aims to establish the feasibility of delivering personalized, brain state-dependent...
This Project Grant award from the National Institute of Child Health and Human Development (CFDA 93.865 - Child Health and Human Development Extramural Research) provides $148,568 to the Rehabilitation Institute of Chicago, doing business as Shirley Ryan AbilityLab, to investigate neuromodulatory strategies for improving paretic leg motor control during walking in individuals with stroke. The key research aims are to: (1) determine the effects of transcutaneous spinal cord stimulation with...
This federal Project Grant award of $465,840.00, titled "INNOVATIVE CLOSED-LOOP FUNCTIONAL ELECTRICAL STIMULATION CONTROL SYSTEM FOR AUGMENTING POST-STROKE GAIT", was awarded by the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research (CFDA 93.865) program. The primary objective is to develop and evaluate a novel data-driven, model predictive functional electrical stimulation (FES) controller that utilizes...
This federal Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) provides $1,167,871 to conduct a randomized controlled trial of long-term home-based transcranial electrical stimulation for improving cognitive and motor function in older adults at risk of developing Alzheimer's disease and related dementias. The primary goal is to evaluate whether transcranial direct current stimulation (tDCS) can induce sustained improvements in dual-task gait performance,...
The federal Project Grant award of $810,000.00 from the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420) supports research on "EARLY NEUROMODULATION FOR COGNITIVE RECOVERY AND REHABILITATION IN TRAUMATIC BRAIN INJURY" at the University of Cincinnati. The grant, awarded on Nov 1, 2024, with a completion date of Oct 31, 2027, will fund scientific investigations exploring innovative approaches to disease prevention, diagnosis, treatment,...
This National Institute of Mental Health (NIMH) Project Grant award under CFDA 93.242 Mental Health Research Grants provides $498,429 to the Children's Research Institute to identify the multi-modal factors that determine individual response to transcranial direct current stimulation (tDCS). The project aims to use state-of-the-art machine learning algorithms to analyze a unique dataset of over 225 concurrent tDCS-functional MRI sessions to determine which factors, such as anatomical...