Project Grant R15EY039555
- The National Eye Institute awarded The University of Chicago $582,115 on September 1, 2026, under the Vision Research program (CFDA 93.867) to investigate the role of lens connexins, cellular stress, and ionic imbalance in cataract formation. The research will define pathogenic mechanisms linking disruption of lens ionic homeostasis and formation of calcium-containing deposits to cataract development. The project utilizes human lens material, mutant mouse models, and in vitro systems to...
- The National Eye Institute, part of the Department of Health and Human Services, awarded Vanderbilt University $435,875 on September 1, 2026, under the Vision Research program (CFDA 93.867) to investigate the mechanism of formation and cataractogenic properties of gamma-S-crystallin cleavage products. The research addresses cataract formation at the molecular level by elucidating how S-crystallin cleavage occurs in aging lenses and the functional consequences of such modification. The work...
- The National Eye Institute awarded the University of Delaware $390,764 on September 1, 2026, under the Vision Research program (CFDA 93.867) to investigate regulatory networks controlling lens development and homeostasis as a means of understanding cataract pathology and prevention. The award funds research on transcriptional and post-transcriptional gene expression control mechanisms in lens development. The recipient will test a hypothesis that ELL2 (elongation factor for RNA polymerase II 2),...
- The National Eye Institute awarded The University of Texas Southwestern Medical Center $456,500 on July 1, 2026, under the Vision Research program (CFDA 93.867, Assistance Listing) for spatial molecular profiling of optic nerve injury and assessment of extracellular matrix (ECM) proteins. The research examines why regenerated retinal ganglion cell (RGC) axons fail to reach the brain after optic nerve injury, instead following circuitous pathways within fibrotic scars—a phenomenon the...
- The National Eye Institute, a division of the Department of Health and Human Services National Institutes of Health, awarded $451,871 to the University of Texas at Austin on September 1, 2026, under the Vision Research program (CFDA 93.867, Assistance Listing program R01EY038362). The award funds research on anticipation and integration in the primate visual system, specifically investigating how temporal prediction shapes neural computation and visual representation. The project will test the...
- The National Eye Institute, a component of the Department of Health and Human Services National Institutes of Health, awarded $513,299 to the University of Texas at Arlington on September 1, 2026, under the Vision Research program (CFDA 93.867) for a Project Grant supporting fundamental research in transcriptional regulation underlying ocular health and disease. The award funds development of TREX, a variational Bayesian framework designed to identify tissue-specific transcriptional regulators...
- The National Eye Institute, part of the Department of Health and Human Services National Institutes of Health, awarded $2,271,828 to The University of Texas Southwestern Medical Center on September 1, 2026, under the Vision Research program (CFDA 93.867). The recipient will conduct research into the cellular and molecular mechanisms governing optic nerve myelin integrity, with emphasis on understanding how myelin whorls—multilayered degenerative myelin structures that appear in demyelinating...
- The National Eye Institute awarded The New England College of Optometry $371,997 on June 1, 2026, under the Vision Research program (CFDA 93.867) to test a novel emmetropization mechanism model based on spectral and spatial opponent information in young children with myopia. The project will investigate how the retina controls eye growth and refraction through a blue-versus-yellow spectral-opponent mechanism. The research tests whether imbalances in retinal spectral and spatial...
- The National Eye Institute awarded The Schepens Eye Research Institute $858,394 on August 1, 2026, under the Vision Research program (CFDA 93.867) to develop multimodal foundation models for eye disease screening and prognosis. The research develops a vision-language foundation model trained on pairs of retinal images and clinical notes to enable downstream supervised models for detection and progression prediction of age-related macular degeneration, diabetic retinopathy, and glaucoma. The...
- Federal Grant Award Summary The National Eye Institute (NEI), under its Vision Research program (CFDA 93.867), awarded a $493,642 Project Grant to the National Opinion Research Center (NORC) on September 1, 2025, with a completion date of August 31, 2027. This project, "Identifying Clusters of Vision and Eye Health Problems Using Secondary Surveillance Data," delivers analytical products designed to address vision and eye health disparities across the United States. The primary...
The National Eye Institute awarded the University of North Texas Research and Innovation Division $564,489 on September 1, 2026, under the Vision Research program (CFDA 93.867) to conduct a large-scale epidemiological study examining occupational chemical and non-chemical exposures in relation to cataract risk. The project, titled "Cataract Risk and Occupational Exposures in Denmark," will extract data from established Danish health registers and apply validated job exposure matrices specific to the Danish work environment to assess occupational exposures associated with cataract development. The study addresses a gap in occupational health research by focusing on understudied workplace exposures linked to cataract outcomes, with findings intended to inform workplace safety policy, advance prevention efforts, and support therapeutic development. Work is performed in Denton, Texas, with a period of performance from September 1, 2026, through August 31, 2027. The award is structured as a Project Grant.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $564.5k | 9/3/26 |