Project Grant R03ES038312
- The National Institute of Environmental Health Sciences awarded the University of New England $163,856 on April 10, 2026, under the Environmental Health program (CFDA 93.113) to conduct a prospective study of per- and polyfluoroalkyl substance (PFAS) mixtures and pregnancy outcomes using data from the Study of Environment, Lifestyle, and Fibroids (SELF). The research leverages an existing cohort of reproductive-aged Black women from Detroit, Michigan, recruited between 2010 and 2012 when...
- The National Institute of Environmental Health Sciences awarded North Carolina State University $4,233,899 under the NIEHS Superfund Hazardous Substances Basic Research and Education program (CFDA 93.143) on August 1, 2026, to evaluate per- and polyfluoroalkyl substances (PFAS) exposure and associated metabolic health effects across three North Carolina communities with contaminated drinking water supplies. The research examines PFAS-induced dyslipidemia and obesity in approximately 1,000...
- The National Institute of Environmental Health Sciences awarded Brigham & Women's Hospital Inc. $4,387,320 on August 5, 2026, under the Environmental Health program (CFDA 93.113) to conduct epidemiological research examining associations between per- and polyfluoroalkyl substances (PFAS) exposure and breast cancer risk in women. The research leverages the Nurses' Health Study, a prospective cohort of 121,701 U.S. women, analyzing paired water and plasma samples collected from approximately...
- The National Institute of Environmental Health Sciences awarded the University of Wisconsin - Madison $3,343,688 on September 1, 2026, under the NIEHS Superfund Hazardous Substances Basic Research and Education program (CFDA 93.143) to examine pathways of per- and polyfluoroalkyl substances (PFAS) exposure and their impacts on hyperlipidemia in a rural community impacted by land spreading of biosolids and sludge. The research addresses three gaps in PFAS science. The study will examine how lipid...
- Federal Project Grant Award Summary Brown University received a $463,850 Project Grant from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health program (CFDA 93.113), awarded on September 10, 2025, with a completion date of September 9, 2027. The award supports research investigating associations between prenatal per- and polyfluoroalkyl substances (PFAS) mixture exposure and long-term health outcomes in adulthood. The research leverages the New England...
- The National Institute of Environmental Health Sciences awarded the University of Massachusetts $752,690 on August 13, 2026, for research on preconception and early pregnancy exposure to endocrine-disrupting chemicals under the Environmental Health grant program (CFDA 93.113). The project investigates how exposure to perfluoroalkyl and polyfluoroalkyl substances (PFAS), polybrominated diphenyl ethers (PBDEs), and trace elements affects women's reproductive health and the ability to achieve...
- The National Institute of Environmental Health Sciences awarded Biota Inc. $306,585 under the Environmental Health grant program (CFDA 93.113) on July 1, 2026, to develop an automated nanoparticle-based sample preparation platform for per- and polyfluoroalkyl substances (PFAS) analysis. The Phase I project establishes feasibility of a fully automated workflow that replaces labor-intensive solid-phase extraction methods in PFAS monitoring. The platform integrates advanced nanoparticle chemistry...
- The National Institute of Environmental Health Sciences awarded George Washington University $158,955 on September 3, 2026, under the Environmental Health program (CFDA 93.113) to develop a place-based framework quantifying drinking water per- and polyfluoroalkyl substances (PFAS) mixture exposure and reproductive health risks. The research addresses the absence of a national framework to estimate drinking water PFAS mixture exposure and evaluate its impact on reproductive health at scale. Aim 1...
- The National Institute of Environmental Health Sciences awarded Virginia Commonwealth University $426,938 on July 1, 2026, under the Environmental Health program (CFDA 93.113) to investigate how lipid transport proteins mediate the biodistribution and accumulation of per- and polyfluoroalkyl substances (PFAS) in human tissues and cells. The three-part research program develops fluorescent and nuclear magnetic resonance binding assays to screen five representative lipid transport proteins against...
- Federal Grant Award Summary The National Institute of Environmental Health Sciences (NIEHS) awarded the University of Massachusetts Lowell $157,437 under the Environmental Health program (CFDA 93.113) on May 10, 2025, for a two-year project concluding May 9, 2027. This Project Grant supports research defining the urinary, biliary, and fecal excretion pathways of diverse per- and polyfluoroalkyl substances (PFAS) and investigating the impact of dietary fiber on PFAS elimination. The research...
The National Institute of Environmental Health Sciences awarded Silent Spring Institute, Inc., $154,700 on August 28, 2026, under the NIEHS Superfund Hazardous Substances Basic Research and Education program (CFDA 93.143) to assess associations between per- and polyfluoroalkyl substance (PFAS) exposure from drinking water and hypertension and blood pressure among adults and children. The project will analyze measured and historically reconstructed serum PFAS concentrations in relation to blood pressure and hypertension outcomes using data from the Agency for Toxic Substances and Disease Registry Multi-Site PFAS Health Study, which encompasses 6,240 adults and 883 children ages 4–17 from communities in eight states with documented PFAS drinking water contamination. Participants provided blood samples, body measurements, and questionnaire responses during 2019–2023. The study will examine effect modification by age, sex, body mass index, and diet, and will assess PFAS mixture effects across varying exposure trajectories over time to address gaps in evidence surrounding PFAS and cardiovascular health outcomes in both adult and pediatric populations. Work is performed in Newtonville, Massachusetts. The period of performance runs from August 28, 2026, through August 27, 2028.
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