Project Grant R01NS146319
- Federal Project Grant Award Summary The University of Miami, through its Office of Research Administration within the School of Medicine, received a $599,005 Project Grant from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award, obligated on August 21, 2025, with a completion date of July 31, 2030, funds fundamental neuroscience research investigating the...
- Federal Project Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $149,264 Project Grant to Indiana University Indianapolis on December 5, 2025, under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. This research initiative, with a completion date of May 15, 2027, investigates the mechanisms by which neutrophils contribute to cognitive decline in a comorbid model of Alzheimer's Disease (AD)...
- Federal Project Grant Award Summary Indiana University Indianapolis received a $435,875 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), awarded September 9, 2025, with an ultimate completion date of July 31, 2030. This award supports fundamental biomedical research investigating the coding and noncoding molecular mechanisms of a bifunctional gene across multiple cellular contexts. The...
- Federal Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded a Project Grant of $123,163 to the Van Andel Research Institute (VAI) on June 1, 2025, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The grant supports research investigating cortical neuronal vulnerability and resilience in Parkinson's disease, with completion targeted for September 26, 2025. The research aims to identify which...
- Federal Project Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded the University of Notre Dame DU Lac a $411,734 Project Grant on August 6, 2025, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to conduct a five-year research investigation into endothelin signaling mechanisms in neural stem cell homeostasis and remyelination. The research will deliver fundamental scientific knowledge...
- Federal Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded $637,820 to the Research Institute at Nationwide Children's Hospital on June 11, 2025, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The project grant supports forward genetic analysis research designed to identify novel genes influencing forebrain neurodevelopment, with specific emphasis on cortical structure, lamination, and...
- Federal Project Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded New Jersey Institute of Technology $553,292 on March 11, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). This three-year project grant, concluding February 28, 2029, supports the development of an in vitro three-dimensional (3D) tissue construct system to study peripheral nerve regeneration and axonal growth. The...
- Federal Project Grant Award Summary The University of Chicago received a $121,230 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853), effective August 1, 2025, through July 31, 2027. This award funds research investigating terminal selector functions in motor neurons, with particular focus on the UNC-3 transcription factor in Caenorhabditis...
- Federal Project Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded The University of Texas Southwestern Medical Center a Project Grant totaling $656,879 under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, effective August 1, 2025, through July 31, 2030. This award supports research investigating the mechanisms of glioma initiation driven by isocitrate dehydrogenase (IDH) oncogenes. The research...
- Federal Project Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded $460,625 to the University of Massachusetts Medical School on June 7, 2025, under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. This exploratory research project, scheduled for completion by May 31, 2027, investigates the roles of the deubiquitylation pathway in TDP-43 (TAR DNA-binding protein 43) pathology relevant to...
Indiana University Indianapolis received a $613,912 Project Grant award dated April 8, 2026, from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award supports research to identify and validate DLK1 as a biomarker for malignant peripheral nerve sheath tumors (MPNST) in patients with neurofibromatosis type 1 (NF1). The research addresses a critical clinical need to develop diagnostic tools capable of identifying peripheral nerve sheath tumors at high risk of malignant transformation, given that current imaging methodologies and biopsy techniques have significant limitations in distinguishing benign from malignant lesions and intermediary atypical neoplasms. The project will be conducted through February 28, 2031, and is expected to deliver research outputs that advance understanding of MPNST tumorigenesis and establish clinical utility of DLK1 as a prognostic biomarker for risk stratification. This research contributes to the NINDS mission of reducing the burden of neurological disease by providing improved diagnostic approaches for a cancer predisposition syndrome affecting approximately 1 in 2,500 individuals worldwide.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $613.9k | 4/7/26 |