Examining a multicomponent intervention to improve HIV health among black men in southern ending the HIV epidemic in the U.S. Jurisdictions

Active Project Grant Awarded Last action

Award ID
R01MH134265
Recipient
Awarding agency
Obligated
$1,074,901

Award facts

Assistance listing
93.242 Mental Health Research Grants
Completion date 66% complete
Funding agency
National Institute of Nursing Research National Institutes of Health, Department of Health and Human Services
Place of performance
Newark, NJ 07107, USA

Award details come from USAspending.gov.

Description

Abstract
Black men who have SEX with men (bmsm) in the U.S. Continue to experience a vastly inequitable HIV burden, particularly in southern ending the HIV epidemic in the U.S. (EHE) jurisdictions. To combat this alarming trend, there is a need for innovative, accessible, and community-developed interventions to promote HIV health among bmsm in these areas. Given research that daily and multilevel intersectional stigma contributes to HIV inequities among bmsm, a multicomponent intervention that addresses multilevel barriers to HIV health and combats intersectional stigma is essential. In collaboration with thrive SS, a leading bmsm- led community-based organization serving bmsm living with HIV in the atlanta area, we developed THRIVE365, an evidence-based multicomponent HIV intervention that provides individual-level health education and motivation, builds social support among bmsm, facilitates access to culturally-affirmative healthcare, and combats barriers to housing and economic empowerment in line with the information- motivation-behavioral skills, social capital, and socioecological models of health. Pilot evidence indicates THRIVE365 is feasible, acceptable, and efficacious in promoting daily antiretroviral treatment (art) adherence and reducing daily depressive symptoms, anxiety symptoms, and emotion regulation difficulties among bmsm living with HIV. THRIVE365 is ready for a full-scale evaluation guided by the RE-aim framework that includes a robust examination of its effectiveness for HIV-related behavioral and psychological outcomes, its moderation effects on intersectional stigma, and its maintenance and reach over time. We will do so with a fully-powered hybrid type 2 implementation-effectiveness trial using daily diary methods, self-report follow-UPS over 6 months, and paradata to examine daily and longer-term intervention engagement, effects, and adaptations. The overarching aims of this research are to: 1) test the effectiveness of THRIVE365 in improving daily and longer-term HIV-related behavioral health (primary outcome: art adherence) and psychological health (e.g., secondary outcomes: lower depressive and anxiety symptoms) in a 6-month waitlist randomized controlled trial with 350 bmsm living with HIV in the four atlanta-area EHE jurisdictions; 2) examine the moderating effect of THRIVE365 on associations between intersectional stigma and our primary and secondary HIV outcomes; 3) evaluate THRIVE365 maintenance and reach at the user-level (e.g., within-user changes in engagement and daily effects) and setting-level (e.g., intervention adaptations, bmsm community uptake). Together, these results will establish the effectiveness of THRIVE365, a community-led, multicomponent intervention, for improving HIV-related behavioral and psychological health among bmsm living with HIV in four of the EHE jurisdictions with the greatest HIV burden. THRIVE365 was designed for implementation and is poised to offer a model for effective HIV care among bmsm in high-stigma, low-resource areas of the U.S. South and beyond.

Transactions

Action Obligated Date
Amendment $260,566
Amendment $175,000
Amendment $289,335
Amendment $175,000
Original award $175,000

Subawards

Subrecipient Amount Awarded
Anastasia Solutions LLC Examining a multilevel mHealth intervention to reduce HIV risk among Black men in the US Deep South $10,700
Emory University $25,893
Emory University $25,893
Naesm, Inc. $300,379
The Trustees Of Columbia University In The City Of New York $18,259
Positive Impact Health Centers Inc. Examining Influences of Place-Based Historical and Contemporary StructuralRacism on Racial Disparities in Aging-Related Disease Risk Trajectories:Leveraging the… $101,873
George Washington University (The) Examining a multilevel mHealth intervention to reduce HIV risk among Black men in the US Deep South $10,700
Positive Impact Health Centers Inc. $102,622
George Washington University (The) $10,820
Naesm, Inc. $204,754
Emory University $26,185
Carnegie-Mellon University $19,017
The Trustees Of Columbia University In The City Of New York $17,927
Positive Impact Health Centers Inc. $110,534
Show all 14

Quick answers

Who received award R01MH134265?

R01MH134265 was awarded to Rutgers The State University Of New Jersey by National Institute of Mental Health (National Institutes of Health) on August 1, 2023.

How much is award R01MH134265 worth?

$1,074,901 has been obligated on R01MH134265.

Which agency awarded R01MH134265?

National Institute of Mental Health (National Institutes of Health) awarded R01MH134265, with funding from National Institute of Nursing Research (National Institutes of Health).

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