Project Grant R01HL185698
- Federal Grant Award Summary The National Institutes of Health, administering funds through the FDA Center for Tobacco Products under the Family Smoking Prevention and Tobacco Control Act Regulatory Research program (CFDA 93.077), awarded The Ohio State University a K01 mentored career development project grant of $186,281 on August 1, 2025, with a completion date of July 31, 2030. This award funds a novel research study investigating the abuse liability and substitutability of synthetic coolants...
- Federal Grant Award Summary The National Heart, Lung, and Blood Institute (NHLBI) awarded the University of California, San Francisco (UCSF) a Project Grant totaling $127,168.00 (Award Date: April 1, 2026; Completion Date: March 31, 2028) under the Cardiovascular Diseases Research program (CFDA 93.837). This research project will model the effects of apolipoprotein L1 (APOL1) genetic risk variants on cardiovascular disease (CVD) risk in African American e-cigarette users using human induced...
- Federal Project Grant Award Summary The National Institute on Drug Abuse (NIDA) awarded $690,741 to the University of Kansas Medical Center Research Institute, Inc. on June 15, 2026, under the Drug Use and Addiction Research Programs (CFDA 93.279) to conduct a rigorous clinical research study evaluating the impact of synthetic cooling agent cigarettes on smoking behavior and abuse liability among adults who smoke menthol cigarettes. The project, scheduled for completion by March 31, 2031, will...
- Federal Project Grant Award Summary Award Details: The National Institute on Drug Abuse (NIDA) awarded a Project Grant of $2.15 million to Wake Forest University Health Sciences on July 1, 2025, under the Drug Use and Addiction Research Programs (CFDA 93.279) for research on the long-term effects of electronic cigarettes on brain health. The performance period extends through March 31, 2030, with the research conducted in Winston-Salem, North Carolina. Research Scope and Deliverables: This...
- Federal Grant Award Summary Health Research, Inc. (Roswell Park Division) received a $816,307 Project Grant award, effective September 15, 2025, through August 31, 2030, under the Family Smoking Prevention and Tobacco Control Act (TCA) Regulatory Research program (CFDA 93.077). This research project, conducted at the awardee's Buffalo, New York facility, generates scientific evidence to inform the Food and Drug Administration's regulatory authority over tobacco products by assessing the market...
- Federal Grant Award Summary West Virginia University received a $931,766 Project Grant from the National Institute on Drug Abuse under the Drug Use and Addiction Research Programs (CFDA 93.279) effective August 1, 2025, through July 31, 2028. The project, "Evaluation of Dependence and Nicotine Replacement Therapy-Supported Cessation Efforts Among Regular Electronic Cigarette Users," addresses a critical gap in research regarding electronic cigarette (e-cigarette) dependence and...
- Federal Grant Award Summary Clemson University's Division of Research received a $353,508 Project Grant award from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) on June 15, 2025, with a completion date of May 31, 2030. This K01 Career Development Award supports an Assistant Professor's research and professional development plan focused on electronic cigarettes (ECs) as a harm reduction strategy for individuals with opioid use...
- Summary of Federal Project Grant Award Wayne State University received a $2.15 million Project Grant from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health program (CFDA 93.113), awarded June 1, 2026, with a completion date of May 31, 2030. The award funds research investigating novel mechanisms by which gestational electronic cigarette (e-cigarette) vaping induces adverse neuronal adaptations in fetal development. The research employs a pregnant...
- Federal Project Grant Award Summary The University of Louisville's Office of Research & Innovation received a $425,987 Project Grant from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health program (CFDA 93.113) to support research into cadmium-induced pulmonary arterial hypertension (PAH) pathogenesis and underlying mechanisms. The project, which commenced on April 23, 2026 and concludes April 22, 2028, will be conducted in Louisville, Kentucky....
- Federal Grant Award Summary Oregon Health & Science University received a $905,044 Project Grant from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) beginning May 1, 2026, and concluding April 30, 2028. This two-year mixed-methods research study will examine current assessment and documentation practices of electronic nicotine delivery systems (ENDS) use in primary care settings across 22 clinics serving over 154,000 patients. The...
The University of Louisville received a $782,293 Project Grant awarded June 10, 2026, through the National Institutes of Health under the Family Smoking Prevention and Tobacco Control Act Regulatory Research program (CFDA 93.077). The grant supports a five-year research initiative (completion date May 31, 2031) investigating the cardiorespiratory and autonomic impacts of coolants used in electronic cigarette aerosols. The research will elucidate how menthol, WS-3, and WS-23—widely used cooling agents in e-cigarettes—alter exposure to harmful constituents, particularly nicotine and aldehydes, while simultaneously affecting cardiovascular and respiratory function. The project will deliver scientific evidence through controlled laboratory research utilizing murine models equipped with continuous electrocardiogram, blood pressure, and pleural pressure telemetry to assess acute and chronic physiological effects. The research will examine how coolant concentration and device power modulate cardiovascular electrophysiology, autonomic tone, ventilatory function, and hemodynamics, with particular attention to age and sex differences in susceptibility. Findings from this regulatory science research will inform Food and Drug Administration policy decisions regarding electronic nicotine delivery system regulation and will address documented public health concerns, including recent case reports of sudden cardiac arrest among young e-cigarette users.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $782.3k | 6/12/26 |