Project Grant R01HL178521
- Federal Project Grant Award Summary Massachusetts General Hospital's Research Management Division received $186,840 in federal funding from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837) for a project titled "Advanced Analysis of High-Resolution Cardiac Diffusion Tensor Images." The award was obligated on July 3, 2026, with a completion date of June 30, 2031. The research deliverables focus on advancing diffusion...
- Federal Grant Award Summary The National Heart, Lung, and Blood Institute (NHLBI) awarded a $429,000 Project Grant to the Regents of the University of Michigan on August 15, 2025, under the Cardiovascular Diseases Research program (CFDA 93.837) to develop a rapid, non-contrast, low-field magnetic resonance imaging (MRI) pipeline for detecting pulmonary embolism (PE). The project, which extends through July 31, 2027, focuses on creating an efficient 3D, contrast-free MRI protocol utilizing...
- Federal Project Grant Summary Beth Israel Deaconess Medical Center, Inc. (BIDMC) received an $848,141 Project Grant from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837), effective July 1, 2026, with a completion date of March 31, 2031. The award funds research to develop and validate cardiac magnetic resonance (CMR) imaging-based diagnostic criteria for coronary microvascular dysfunction (MVD)—a condition affecting up to...
- Federal Project Grant Summary Award Details: Pulseimaging.ai, LLC received $304,415 in federal funding under the National Heart, Lung, and Blood Institute's (NHLBI) Cardiovascular Diseases Research program (CFDA 93.837). The award was obligated on August 15, 2025, with a completion date of August 14, 2027. Products and Services: The awardee will develop an artificial intelligence-enabled software solution designed to predict future cardiovascular events from screening CT calcium score (CTCS)...
- Federal Grant Award Summary Brigham & Women's Hospital Inc. received a $201,426 Project Grant from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837), effective September 1, 2025, through August 31, 2030. This training program in patient-oriented research in cardiovascular endocrinology provides comprehensive, curriculum-based training designed to address the documented decline in clinical investigators since 2000. The...
- Federal Project Grant Award Summary Northwestern University's Sponsored Research Division received a $1.597 million Project Grant from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837), awarded July 1, 2026, with completion targeted for December 31, 2027. The grant supports basic research investigating mitochondrial quality control mechanisms in cardiac allograft vasculopathy (CAV), a significant complication limiting long-term...
- Federal Project Grant Award Summary Massachusetts General Hospital's Research Management Division received a $867,656 Project Grant from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837), awarded on May 1, 2026, with a completion date of February 28, 2031. The award funds research to determine the effectiveness of guideline-directed medical therapies (GDMT) for heart failure with mildly reduced ejection fraction (HFmrEF)—a...
- Federal Project Grant Award Summary The National Heart, Lung, and Blood Institute (NHLBI) awarded a $763,046 Project Grant to the Regents of the University of Minnesota on July 15, 2026, under the Cardiovascular Diseases Research program (CFDA 93.837) to develop and validate a rapid cardiac magnetic resonance imaging (CMR) protocol for heart failure diagnosis. The primary deliverable is a clinically optimized CMR examination protocol that reduces scan time from 45-60 minutes to approximately...
- Federal Grant Award Summary Massachusetts General Hospital's Research Management Division received a $1,519,316 Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837), effective September 1, 2025, through June 30, 2029. The award funds development and clinical validation of mechanomicroscopy, an innovative endoscopic imaging platform designed to enable transbronchial assessment of pulmonary hypertension (PH)...
- Federal Project Grant Award Summary Northwestern University received a $684,570 Project Grant from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837), effective July 1, 2026, through April 30, 2030. The award funds translational research and development of a bioengineered mitochondrial therapy platform designed to address endothelial injury and dysfunction in vascular surgery. The research deliverables include optimization of...
Federal Grant Award Summary The National Heart, Lung, and Blood Institute (NHLBI) awarded Endeavor Health Clinical Operations (doing business as Evanston Hospital) a $1.55 million Project Grant under the Cardiovascular Diseases Research program (CFDA 93.837) for the period July 15, 2026 through March 31, 2028. The funded research project, "Improved Cardiovascular MRI Using Equilibrium Phase BT1RESS MR Angiography," develops and validates an advanced magnetic resonance imaging technique designed to generate high-quality angiographic images during the equilibrium phase of contrast enhancement. The deliverables include technical development and clinical validation of the balanced T1 relaxation-enhanced steady-state (BT1RESS) pulse sequence across two collaborative research sites, with specific focus on comparing imaging quality, signal characteristics, and contrast-agent dosing efficiency relative to conventional contrast-enhanced MR angiography (CEMRA) in healthy subjects and patients with cardiovascular disease. The project addresses a significant clinical limitation in current angiographic imaging: conventional techniques produce degraded image quality after the initial contrast bolus passes due to agent dilution. The BT1RESS methodology extends high-quality imaging windows from tens of seconds to tens of minutes post-contrast administration while enabling reduced contrast doses, offering particular clinical value for patients with renal impairment who cannot tolerate iodinated contrast agents required for computed tomography angiography (CTA). Deliverables from this five-year initiative will include technical specifications, clinical validation protocols, and evidence supporting the incorporation of equilibrium phase BT1RESS into cardiovascular imaging practice.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $1.6m | 7/9/26 |