The National Heart, Lung, and Blood Institute (NHLBI) awarded a $2,070,206 Project Grant under the Cardiovascular Diseases Research program (CFDA 93.837) to the Ann & Robert H. Lurie Children's Hospital of Chicago. The 4-year grant, effective August 15, 2024, will fund research to characterize the "endotypes" or subtypes of bronchopulmonary dysplasia (BPD) in premature infants. The research will leverage existing data from approximately 2,000 former preterm infants enrolled in prospective studies to perform genetic meta-analysis and integrate genetic, physiologic, and longitudinal clinical data. The goal is to provide criteria for early diagnosis of respiratory disease subtypes in premature infants to enable development of personalized, mechanism-based interventions to prevent or treat these long-term respiratory complications. The Ann & Robert H. Lurie Children's Hospital of Chicago has extensive experience managing federal grants and contracts for pediatric healthcare research and services.
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