The 3E study: economic and educational contributions to emerging adult cardiometabolic health

Active Project Grant Awarded Last action

Award ID
R01HL160703
Recipient
Awarding agency
Obligated
$7,597,632

Award facts

Assistance listing
93.837 Cardiovascular Diseases Research
Completion date 77% complete
Originally
Place of performance
Bronx, NY 10458, USA

Award details come from USAspending.gov.

Description

As the agency reported it.

Abstract
Adverse childhood experiences (ACES) may contribute to inequities in cardiometabolic health disproportionately experienced by latinx emerging adults. With the increased use of ACE measures in health research, there is a need to consider how well the measures work in diverse populations and whether ACES categories need to be expanded to include community-level adversity. First, although existing ACE measures have been used to understand how adversity early in life impacts the adoption of risky health behaviors and long-term health, the original measures were developed with a population that had health insurance and was largely white and well-educated; they do not necessarily reflect the diversity of adverse childhood experiences that may be disproportionately experienced by some communities (e.g., immigration-related traumas, policing-related traumas). More work needs to be done to understand how applicable they are to more diverse populations. Second, DR. Felitti's original ACES measures, typically referred to as "conventional ACES," were focused on household-level adversity (psychological, physical or sexual abuse; domestic violence against the mother; or living with household members who were substance abusers, mentally ILL or suicidal, or ever imprisoned). Increasingly, researchers recognize that experiences outside the home also shape the lives of children and influence health and health behavior, especially for people from minoritized racial/ethnic groups and/or those living in poverty, and are calling for expanded ACE measures that address interpersonal and community-level adversity. Expanded ACE measures can include experiences of poverty, racism, discrimination, bullying, immigration-specific adversity, and community violence. In addition to expanding ACES to include community level adversity, IT may be useful to consider the framework of resilience or positive childhood experiences. Narayan ET AL. Developed the benevolent childhood experiences (BCE) scale that focuses on promotive factors. Measures include positive experience with parents, peers, teachers, and extended social networks, a supportive environment, and a predictable routine. The objectives of this diversity supplement are 1) to develop an ACE scale specific to community level stressors (poverty, racism, discrimination, bullying, immigration specific adversity and community violence), 2) to quantify ACES and bces in the 3E study's cohort of diverse emerging adults, and 3) to use qualitative methods to document and contextualize how adversity impacts cardiometabolic behaviors (diet, physical activity, sleep, and smoking) and cardiometabolic health (weight and blood pressure). The evidence generated from this work could inform future community-level interventions targeting determinants of cardiometabolic health and will position the candidate to have an impactful career as an independent researcher investigating the impact of community level adverse childhood experiences on cardiometabolic health in diverse populations.

Transactions

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Original award $683,227
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Subawards

Subrecipient Amount Awarded
California State University, East Bay Foundation, Inc. Dr. Gamba will participate in all aims of the project. He will also have specific designated responsibilities, including supervising data collection for the… $5,358
The Regents Of The University Of California Dr. Ream will serve as Co- Investigator on this project, Dr. Ream’s role will be to design materials, train staff, coordinate data collection, and collaborate… $194,701
The Leland Stanford Junior University David Rehkopf is a social epidemiologist and serves as an Associate Professor in the Department of Epidemiology and Population Health. His areas of expertise… $72,732
The Regents Of The University Of California. San Francisco As MPI, Cohen will be responsible for the overall administration of this project and she will share responsibility for the substantive direction of the… $90,093
California State University, East Bay Foundation, Inc. Dr. Gamba will participate in all aims of the project. He will also have specific designated responsibilities, including supervising data collection for the… $37,361
The Leland Stanford Junior University David Rehkopf is a social epidemiologist and serves as an Associate Professor in the Department of Epidemiology and Population Health. His areas of expertise… $39,024
The Regents Of The University Of California Dr. Ream will be to design materials, train staff, coordinate data collection, and collaborate on analyses and sharing of findings. $98,590
California State University, East Bay Foundation, Inc. Dr. Gamba will participate in all aims of the project. He will also have specific designated responsibilities, including supervising data collection for the… $62,308
California State University, East Bay Foundation, Inc. This is a diversity supplement for Cristina Zavala. Ms. Zavala will provide input from the perspective of a student to the recruitment plan and materials and… $40,380
The Regents Of The University Of California. San Francisco As MPI, Cohen will be responsible for the overall administration of this project and she will share responsibility for the substantive direction of the… $133,304
The Leland Stanford Junior University David Rehkopf is a social epidemiologist and serves as an Associate Professor in the Department of Epidemiology and Population Health. His areas of expertise… $40,144
The Regents Of The University Of California Dr. Ream will be to design materials, train staff, coordinate data collection, and collaborate on analyses and sharing of findings. $79,416
Bakersfield Auxiliary For Sponsored Programs Administration California State University This is a diversity supplement for Andrea Lopez. Dr. Lopez will be responsible for conducting pyschometric analysis of current community level ACE measures. She… $139,275
Bakersfield Auxiliary For Sponsored Programs Administration California State University $44,403
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Quick answers

Who received award R01HL160703?

R01HL160703 was awarded to Fordham University by National Heart Lung and Blood Institute (National Institutes of Health) on December 29, 2022.

How much is award R01HL160703 worth?

$7,597,632 has been obligated on R01HL160703.

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