Racial/ethnic disparities in heart failure: a cross cohort collaboration
Ended Project Grant Awarded Last action
- Award ID
- R01HL150170
- Recipient
-
Kent County Memorial Hospital UEI NPXGTX5G5C74 Part of Care New England Health System
- Awarding agency
-
National Heart Lung and Blood Institute
National Institutes of Health, Department of Health and Human Services
- Obligated
- $4,747,177
Award facts
- Assistance listing
- 93.837 Cardiovascular Diseases Research
- Completion date
- Originally
- Place of performance
- Rhode Island, USA
Award details come from USAspending.gov.
Description
- Abstract
- Heart failure (HF), and its subtypes defined by preserved (HFPEF), reduced (HFREF) or mid-range (HFMREF) ejection fraction are a major and growing public health problem. The long term goal of this project is to better understand the health disparities regarding HF and define effective preventive measures that may reduce these disparities. We propose to pool data from 10 large longitudinal cohort studies to examine race/ethnic and SEX disparities in developing HF, its subtypes, and its prognosis. The harmonized data will include over 130,028 men and women with over 8975 similarly-adjudicated prospective HF outcomes, representing a wide spectrum of ages, race/ethnicities, and geographic regions of the united states. This cross-cohort collaboration will provide a unique opportunity to conduct a comprehensive evaluation of SEX and racial/ethnic health disparities in HF. Causal mediation analysis techniques will be used to estimate the degree to which single and multi-factor lifestyle and clinical interventions could potentially reduce health disparities in HF. In our phenomapping aim, we will define unique clinically relevant phenotypes of HF based upon cohort data that is also commonly present in medical records for enhanced generalizability, including age, race/ethnicity, SEX, clinical signs, symptoms, biomarkers, ejection fraction, physiologic measures, and CO-morbidities; we will also evaluate HF phenotype associations with CVD and all-cause mortality.
Transactions
| Action | Obligated | Date |
|---|---|---|
| Amendment | $0 | |
| Amendment | $53,111 | |
| Amendment | $597,498 | |
| Amendment | $597,498 | |
| Amendment | $679,452 | |
| Amendment | $679,452 | |
| Amendment | $679,452 | |
| Amendment | $69,466 | |
| Amendment | $625,167 | |
| Amendment | $0 | |
| Original award | $766,081 |
Show all 11
Subawards
| Subrecipient | Amount | Awarded |
|---|---|---|
| Northwestern University | $2,377 | |
| Northwestern University | $11,370 | |
| The Research Foundation For The State University Of New York | $22,422 | |
| University Of Alabama At Birmingham | $35,866 | |
| Brown University | $137,615 | |
| The Regents Of The University Of California. San Francisco | $10,901 | |
| Northwestern University | $64,330 | |
| University Of Mississippi Medical Center | $37,064 | |
| The Research Foundation For The State University Of New York | $39,100 |
Quick answers
Who received award R01HL150170?
R01HL150170 was awarded to Kent County Memorial Hospital by National Heart Lung and Blood Institute (National Institutes of Health) on March 26, 2021.
How much is award R01HL150170 worth?
$4,747,177 has been obligated on R01HL150170.
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