Project Grant R01HG014032
- Federal Project Grant Award Summary New York University School of Medicine received a $466,125 Project Grant from the National Human Genome Research Institute (NHGRI) under the Human Genome Research program (CFDA 93.172), awarded on May 18, 2026, with a completion date of April 30, 2028. The award funds a cross-species analysis of regulatory genomic function utilizing synthetic regulatory genomics and the BIG-IN (in situ) genome engineering technology platform. The research will characterize the...
- Federal Grant Award Summary The National Human Genome Research Institute (NHGRI) awarded Fred Hutchinson Cancer Center a $2.41 million Project Grant on September 19, 2025, under the Human Genome Research program (CFDA 93.172) to develop an experimental-data-based in-silico data generation platform for improving single-cell and spatial omics analysis. The project, extending through August 31, 2029, will deliver three integrated products: (1) statistical methods and tools to generate in-silico...
- Federal Grant Award Summary The Children's Hospital of Philadelphia Research Institute, in collaboration with Massachusetts Institute of Technology, is conducting fundamental genomics research funded by the National Human Genome Research Institute (NHGRI) under the Human Genome Research program (CFDA 93.172). This $863,248 Project Grant, awarded February 1, 2026, and extending through January 31, 2030, investigates three-dimensional (3D) chromatin architectural dynamics at ultra-high...
- Federal Project Grant Award Summary The National Human Genome Research Institute (NHGRI) awarded $789,739 to the Sloan-Kettering Institute for Cancer Research on September 19, 2025, under the Human Genome Research program (CFDA 93.172) to develop innovative approaches for engineering transcriptional states in fibroblasts and other differentiated cell types through September 2029. The award supports the transformation of Perturb-seq into a systematic platform for rationally reconstructing diverse...
- Federal Project Grant Award Summary Boston Medical Center Corporation has been awarded $3,371,645 by the National Human Genome Research Institute (NHGRI) under the Human Genome Research program (CFDA 93.172) to develop scalable software engineering methods and computational tools for large-scale subcellular spatial omics analysis. The four-year project, initiated September 1, 2025, and concluding August 31, 2029, addresses critical barriers in spatial subcellular transcriptomics research by...
- Federal Project Grant Award Summary The University of Chicago received a $581,259 Project Grant award from the National Human Genome Research Institute (NHGRI) under the Human Genome Research program (CFDA 93.172), effective August 20, 2025, with a completion date of June 30, 2029. This award supports the development of novel methodologies for transcriptomic characterization of membraneless organelles (MLOs)—subcellular structures ranging from 1-200 nanometers to several microns that organize...
- Federal Project Grant Award Summary The National Human Genome Research Institute (NHGRI) awarded Icahn School of Medicine at Mount Sinai a Project Grant totaling $2.58 million (awarded April 13, 2026; completion date March 31, 2030) under the Human Genome Research program (CFDA 93.172) to develop computational tools and analytical frameworks for characterizing tissue microenvironment organization using spatial omics data. The award funds development of ONTRAC (a niche trajectory analysis...
- Federal Project Grant Award Summary Carnegie Mellon University received a $4.51 million Project Grant from the National Human Genome Research Institute (NHGRI) under the Human Genome Research program (CFDA 93.172), effective June 1, 2026 through May 31, 2030. The award funds the development of advanced computational methods to fine-map genome-wide association study (GWAS) disease mechanisms through integration of multi-modal functional genomics data. The research team will create novel...
- The National Human Genome Research Institute (NHGRI), under the Human Genome Research Federal Grant Program (CFDA 93.172), awarded a $384,418 Project Grant to Xgenomes Corp. on September 25, 2024 to develop a revolutionary DNA sequencing platform. The project aims to create a super-resolution single-molecule sequencing technology that can read short sequence "words" rather than individual nucleotides, enabling one or more orders of magnitude improvements in accuracy and cost over...
- Federal Grant Award Summary The National Human Genome Research Institute (NHGRI), under the Human Genome Research program (CFDA 93.172), awarded $249,000 to the Regents of the University of California at Riverside on September 23, 2025, for a three-year project extending through August 31, 2028. This Project Grant supports the development and application of an innovative laser particle-based cell barcoding technology designed to enable simultaneous tracking of live cells and acquisition of...
The National Human Genome Research Institute (NHGRI), operating under the Human Genome Research program (CFDA 93.172), awarded $2.68 million to the New York Genome Center, Inc. on June 22, 2026, for the development of NextGen Spatial Multi-Omics Technologies. The project, which runs through May 31, 2030, focuses on creating the first cost-effective, user-friendly platform for spatial multi-omic profiling in tissue samples. This technology addresses a critical gap in current genomic research capabilities by enabling simultaneous measurement of multiple molecular modalities—including chromatin states, transcriptional activity, RNA processing, and post-translational modifications—while maintaining spatial resolution within tissue architecture. The project will overcome existing technical and financial barriers by developing innovative fabrication techniques and ensuring that each new capability can function independently to enhance existing spatial technologies or operate as an integrated platform. The award recognizes the awardee's extensive expertise in advanced genomic sequencing services and multi-omic technology development. New York Genome Center's work under this grant will advance fundamental understanding of how gene regulatory networks and cellular microenvironments influence tissue organization and function, with applications across multiple disease areas and precision medicine initiatives. The resulting platform is expected to provide the research community with accessible tools for spatial multi-omic analysis without prohibitively expensive consumables or specialized capital equipment requirements.Federal Project Grant Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $2.7m | 6/26/26 |