Project Grant R01HD125923
- The National Institute of General Medical Sciences, part of the National Institutes of Health within the Department of Health and Human Services, awarded Texas Tech University Health Sciences Center $492,625 under CFDA 93.859 (Biomedical Research and Research Training) on September 1, 2026, to support research on quality control pathways governing protein translocation and folding in the endoplasmic reticulum. The research focuses on understanding molecular mechanisms regulating protein movement...
- The National Institute of Environmental Health Sciences awarded $124,107 to the University of Texas at Austin on September 1, 2026, under the Environmental Health program (CFDA 93.113) to conduct research on extracellular vesicles as mediators of epigenetic changes induced by environmental endocrine-disrupting chemicals in male reproductive health. The research investigates how exposure to endocrine-disrupting chemicals modifies epididymosome cargo—specifically small non-coding RNA...
- The National Institute of Child Health and Human Development awarded The University of Texas Southwestern Medical Center $500,118 on August 15, 2026, under the Child Health and Human Development Extramural Research program (CFDA 93.865) to conduct research on the molecular control of endoplasmic reticulum remodeling during spermiogenesis. The research investigates how spermatids compact the endoplasmic reticulum (ER), the largest intracellular organelle, during the morphological transformation...
- The National Institute of Child Health and Human Development, part of the Department of Health and Human Services National Institutes of Health, awarded $440,000 to the University of Texas Medical Branch at Galveston on August 15, 2026, under the Child Health and Human Development Extramural Research program (CFDA 93.865). The award funds research to evaluate mechanistic pathways through which heat exposure during pregnancy triggers preterm birth, addressing a knowledge gap in understanding...
- The National Institute of Child Health and Human Development, part of the Department of Health and Human Services National Institutes of Health, awarded $456,500 to The University of Texas Southwestern Medical Center on June 1, 2026, under the Child Health and Human Development Extramural Research program (CFDA 93.865). The award funds molecular characterization of human pregnancy-induced cervical epithelium through two research aims. First, the recipient will apply single-cell and spatial...
- The National Institute of Child Health and Human Development awarded The University of Texas Southwestern Medical Center $682,848 on June 1, 2026, under the Child Health and Human Development Extramural Research program (CFDA 93.865) to investigate mitochondrial function and quality control in germ cell development and reproductive aging. The award funds basic biomedical research using a novel enforced mitophagy platform to modulate mitochondrial abundance and quality in vivo across specific...
- The National Institute of General Medical Sciences (NIGMS), part of the Department of Health and Human Services National Institutes of Health, awarded the University of Texas at Dallas $435,875 on June 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859, Assistance Listing) to investigate how tissue-specific progenitor cell fate is governed by mesenchymal progenitors and sympathetic neurons during adult tissue regeneration. The recipient will use the postnatal mouse...
- The National Institute of Child Health and Human Development awarded The University of Texas at San Antonio $124,590 on July 1, 2026, under the Child Health and Human Development Extramural Research program (CFDA 93.865) to support research on the local regulation of signaling isoprenoids in gonad development. The funded research investigates how juvenile hormone signaling is spatiotemporally regulated during embryonic ovary and testis development in Drosophila melanogaster. The project...
- The National Institute of Child Health and Human Development awarded Trustees of Tufts College (doing business as Tufts University School of Medicine) $453,750 on June 1, 2026, under the Child Health and Human Development Extramural Research program (CFDA 93.865) to investigate epigenetic inheritance of trauma effects through sperm microRNA changes. The research examines how trauma exposure in men correlates with altered microRNA profiles in sperm—specifically elevated levels of miRNAs 532, 361,...
- The National Institute of General Medical Sciences awarded Texas A&M University System Health Science Center $420,657 on July 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859, assistance type Project Grant) to support research on nanoscale structure and dynamics within nuclear pores and condensates. The funded research examines intrinsically disordered proteins and regions in the proteome, with focus on transport properties of the nuclear pore complex and...
The Department of Health and Human Services National Institutes of Health Office of the Director awarded Texas Tech University Health Sciences Center $575,904 on September 1, 2026, under the Trans-NIH Research Support program (CFDA 93.310) to investigate protein-based transgenerational inheritance in mammals. The funded research examines how paternal environmental exposures transmit phenotypic changes to offspring across generations, with focus on establishing germ granules consisting of epigenetic modifying amyloids as the information carriers in mammalian sperm that convey environmental signals and corresponding phenotypes to offspring. The research builds on evidence that paternal exposures—including endocrine disruptors, nutritional stress, and dietary composition—produce measurable phenotypic effects in descendants, and seeks to determine the precise mechanisms by which spermatozoa incur and transmit transgenerational effects beyond classical epigenetic mechanisms such as DNA methylation, chromatin remodeling, and small noncoding RNAs. The award covers the period from September 1, 2026, through July 31, 2031, with place of performance in Lubbock, Texas.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $575.9k | 8/7/26 |