Project Grant R01HD120132
- This $747,000 Project Grant award from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) will fund research to determine the effects of pre-exposure prophylactic (PrEP) drugs on female genital HIV infection and women's reproductive health. The research will focus on understanding how PrEP impacts the female reproductive tract microenvironment and any potential...
- This Project Grant award from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) provides $588,566 to the University of Maryland, Baltimore to conduct a cross-disciplinary study on the long-term neurodevelopmental and school readiness impacts of in-utero HIV exposure on children in Sub-Saharan Africa. The research aims to establish a core team of investigators who can...
- This Project Grant award from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), will support a mixed methods research study to investigate the social and behavioral drivers of HIV risk among South African adolescent girls and young women (SA-AGYW). The $244,814 award, effective March 14, 2025 through May 15, 2028, will enable the awardee, the University of...
- The National Institute of Child Health and Human Development (NICHD) awarded a $2,207,322 Project Grant under the Child Health and Human Development Extramural Research program (CFDA 93.865) to the University of Nebraska Medical Center to develop dose flexible, ultra-long-acting prodrug formulations for antiretroviral therapy (ART) in pediatric HIV patients. The goal is to create a complete every 6-month integrase strand transfer inhibitor (INSTI)-based ART regimen, including bictegravir,...
- This Cooperative Agreement award of $2,052,694 from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) is funding a multi-country research project titled "Researching Interventions and Implementation Strategies to Evaluate the Health and Development of Children Affected by HIV in Southern and Eastern Africa (RISE)". The key products and services being...
- The Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) awarded a $232,500 Project Grant under the Child Health and Human Development Extramural Research program (CFDA 93.865) to The Johns Hopkins University. The grant supports research to investigate the virologic determinants that lead to long-term antiretroviral therapy-free control in a subset of infants infected with HIV-1 in utero. Key research activities include: Creating infectious molecular clones...
- The National Institute of Child Health and Human Development (NICHD) awarded a $258,556 Project Grant under the Child Health and Human Development Extramural Research program (CFDA 93.865) to The Johns Hopkins University for a longitudinal study on the association of lifelong antiretroviral treatment (ART) with anti-Mullerian hormone (AMH) levels and fecundability in women living with HIV in Malawi. The study aims to assess the impact of long-term ART on reproductive hormones and fertility...
- This federal Project Grant award of $709,872 from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) aims to develop and pilot test a couple-based intervention to address perinatal depression and improve adherence to prevention of mother-to-child transmission (PMTCT) of HIV in Malawi. The key objectives are to: 1) develop a couple-based intervention using problem-solving therapy and content on couple...
- This Project Grant award from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) provides $680,644 to the University of Alabama at Birmingham (UAB) to evaluate the "Healthy Families-PREP" intervention. This intervention aims to promote the use of pre-exposure prophylaxis (PrEP) among periconception, pregnant, and postpartum women in rural Uganda to reduce HIV incidence. The 5-year project will first adapt the 3-session...
- This federal Project Grant award from the National Institute of Allergy and Infectious Diseases (CFDA 93.855 - Allergy and Infectious Diseases Research) provides $381,487 to the University of Maryland, Baltimore (UMB) to assess the early implementation of long-acting injectable cabotegravir (CAB-LA) pre-exposure prophylaxis (PrEP) among adolescent girls and young women (AGYW) at high risk of HIV acquisition in Zambia. The key objectives are to: 1) Evaluate implementation determinants of CAB-LA...
This $499,140 Project Grant award from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) will fund the "TSEPAMO NEXT GENERATION: OPTIMIZING HIV TREATMENT AND PREVENTION STRATEGIES FOR PREGNANT WOMEN IN BOTSWANA" research study. The study has two key aims: 1) to assess the safety and efficacy of two-drug antiretroviral therapy (ART) with dolutegravir/lamivudine (DTG/3TC) for pregnant women living with HIV, and 2) to identify drivers of new HIV infections among pregnant women in Botswana and evaluate the potential for long-acting pre-exposure prophylaxis (PrEP) in this population. The research will be conducted by the Harvard T.H. Chan School of Public Health, leveraging the existing TSEPAMO surveillance infrastructure in Botswana, with the goal of informing international HIV treatment and prevention guidelines for pregnant women.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $499.1k | 9/15/25 |