Project Grant R01HD117115
- The National Institute of Child Health and Human Development awarded Massachusetts General Hospital $466,740 on August 3, 2026, under the Child Health and Human Development Extramural Research program (CFDA 93.865) to investigate congenital diaphragmatic hernia (CDH) using fetal tracheal aspirates as a molecular and cellular window into hypoplastic lung development. The project will examine when an inflammatory signature—characterized by increased cytokeratin 5 and activated NFKB expression with...
- The National Institute of Child Health and Human Development awarded Cincinnati Children's Hospital Medical Center $165,240 on June 1, 2026, under CFDA 93.865 (Child Health and Human Development Extramural Research) to investigate the effects of bioactive components in donor milk on preterm infant growth, addressing suboptimal postnatal growth in very low birth weight premature infants. The project runs through May 31, 2030, with performance in Cincinnati, Ohio. The award is classified as a...
- The National Institute of Child Health and Human Development awarded The Ohio State University $315,000 on June 16, 2026, under the Child Health and Human Development Extramural Research program (CFDA 93.865) to characterize respiratory-swallow coordination patterns in individuals with chronic post-stroke dysphagia and evaluate their relationship to physiological and patient-centered swallowing outcomes. The research addresses dysphagia occurring in up to 78 percent of individuals during acute...
- The Department of Health and Human Services National Institute of Child Health and Human Development awarded Loyola University of Chicago Health Sciences Campus $1,025,913 on September 10, 2025, under the Child Health and Human Development Extramural Research program (CFDA 93.865) to conduct a randomized controlled trial of multisensory early oral administration of human milk for very preterm infants, with the goal of enhancing stress regulation, neurodevelopment, and oral feeding skills. The...
- The National Heart, Lung, and Blood Institute awarded the University of North Carolina at Chapel Hill $200,137 on September 1, 2026, under the Cardiovascular Diseases Research program (CFDA 93.837) to develop non-invasive tools for assessing aspiration risk in infants with swallowing dysfunction. The project will refine and validate clinical scoring tools based on observable feeding variables and develop artificial intelligence-enabled cervical auscultation methods to detect aspiration during...
- The National Institute of Child Health and Human Development awarded Case Western Reserve University $431,750 on September 1, 2026, under the Child Health and Human Development Extramural Research program (CFDA 93.865) to support research on proteolytic cleavage of PR-B as a novel mechanism for functional progesterone withdrawal in human parturition, with specific focus on spontaneous preterm birth. Work is performed in Cleveland, Ohio through August 31, 2028. The recipient's Office of...
- The National Institute of Child Health and Human Development awarded The Ohio State University $157,500 on September 1, 2026, under the Child Health and Human Development Extramural Research program (CFDA 93.HDR) to evaluate the dynamics of developmental tube morphogenesis. The recipient will construct and validate a computational framework combining mathematical modeling and image-based analysis to investigate how mechanical forces and genetic regulation coordinate biological tube formation and...
- The National Institute of Child Health and Human Development awarded Cincinnati University's Sponsored Research Services Division $461,000 on September 1, 2026, under the Child Health and Human Development Extramural Research program (CFDA 93.865). The award funds PREEMIE PROGRESS 3.0, a family management program designed to meet parents of very preterm infants' needs through comprehensive intervention teaching complex infant care, offering psychosocial support, and providing resources to...
- The National Institute of Child Health and Human Development awarded Boston College $459,704 on September 5, 2026, under the Child Health and Human Development Extramural Research program (CFDA 93.865) to conduct a pilot study adapting a parent-facilitated early oral-sensory feeding intervention for preterm infants in neonatal intensive care units. The award funds development and evaluation of the Parent-Facilitated Early Oral-Sensory Experience (PEOE) Program, which trains parents using a...
- The National Institute of Child Health and Human Development awarded Case Western Reserve University $472,336 on September 3, 2026, under the Child Health and Human Development Extramural Research program (CFDA 93.865) to investigate long-term neurodevelopmental outcomes in pediatric intensive care unit (PICU) survivors using standardized school assessment scores. The research (KRASHER—Kindergarten Readiness Assessment Scores after Having Early-Childhood Respiratory Failure) uses kindergarten...
The National Institute of Child Health and Human Development awarded Northeast Ohio Medical University $626,200 on August 20, 2026, under the Child Health and Human Development Extramural Research program (CFDA 93.865) to investigate the impact of aspiration on lung pathophysiology in animal models of term and preterm infants. The recipient will develop a predictive model linking feeding physiology, blood biomarkers, and aspiration frequency to measurable changes in lung pathophysiology. The work includes quantifying responses to varying aspiration levels in term and preterm infant models on normal and thickened milk, using high-resolution videofluoroscopy, histological assays, and in vivo blood biomarkers of inflammation to measure aspiration-driven lung damage. The project tests the hypothesis that a dose relationship exists between aspiration frequency and extent and histologically measurable lung damage, and examines whether physiologic measurements and lung-clearing ability contribute to pulmonary damage. Performance occurs in Rootstown, Ohio. The award runs through May 31, 2031.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $626.2k | 8/24/26 |