An integrated intervention to address the double burden of maternal child malnutrition in guatemala

Active Project Grant Awarded Last action

Award ID
R01HD114708
Recipient
Awarding agency
Obligated
$1,757,821

Award facts

Completion date 38% complete
Place of performance
Boston, MA 02115, USA

Award details come from USAspending.gov.

Description

As the agency reported it.

Abstract
Globally, populations are experiencing increases in diseases attributable to overnutrition, but child undernutrition also persists at high levels. This "double burden of malnutrition" commonly appears as maternal overweight/obesity and child stunting in the same household. Poor nutrition during the critical life stages of the pregnancy, the postpartum period, and early childhood increases life-long risk for nutrition-related non- communicable diseases such as diabetes, hypertension, and dyslipidemia for both mother and child. Evidence- based interventions exist that promote optimal weight gain during pregnancy and postpartum weight loss or prevent undernutrition among children, but little is known about implementing them as integrated, scalable, intergenerational, affordable, and equity-focused solutions. The overall goal of this project is to assess the effectiveness, implementation, and cost-effectiveness of an integrated intervention to reduce the double burden of malnutrition among pregnant/postpartum women and their children. We will conduct a type 1 hybrid effectiveness-implementation trial in rural guatemalan indigenous communities that have among the world's highest prevalence of the double burden of malnutrition. Our project will have three parts. In part 1, we will conduct an individually randomized hybrid type 1 effectiveness-implementation trial with 766 pregnant mothers and their children, including both food supplementation and counselling to optimize mothers' gestational weight gain and limit postpartum weight retention. Our primary evaluation will focus on maternal weight and child length at 12 months after birth. In part 2, we will assess barriers and facilitators to implementation of the integrated DBM intervention and develop strategies to promote widespread implementation. In part 3, we will conduct an economic evaluation on the integrated nutrition intervention. To our knowledge, this aim will generate the first evidence of costs and cost-effectiveness of interventions to address DBM at the household level, providing crucial information to policymakers and stakeholders for future implementation and budgeting. Overall, this project will generate globally relevant implementation evidence on interventions for the double burden of malnutrition. Results will have implications for nutrition and NCD policy not only in guatemala but also globally. A major feature of the project is a focus on pragmatism and equity, working to enroll the most vulnerable families from rural guatemala who stand most to benefit from the intervention but who are commonly excluded from clinical trials.

Transactions

Action Obligated Date
Amendment $104,412
Amendment $370,115
Amendment $641,647
Original award $641,647

Subawards

Subrecipient Amount Awarded
Instituto De Nutricion De Centro America Y Panama he Institute of Nutrition of Central America and Panama (INCAP) will take overall responsibility for the supervision and coordination of field data collection… $104,412
University Of Missouri System The overall goal of this project is to assess the effectiveness, implementation and cost-effectiveness of an intervention to reduce the double burden of… $36,531
President And Fellows Of Harvard College Dr. Miller will assist in the design and implementation of the study, including sample size and power calculations, the randomization scheme, and the analysis… $43,559
Instituto De Nutricion De Centro America Y Panama The Institute of Nutrition of Central America and Panama (INCAP) will take overall responsibility for the supervision and coordination of field data… $141,641
Wuqu' Kawoq, S.A. Through this statement of work, Wuqu’ Kawoq expresses its interest in collaborating with the project entitled: “An integrated intervention to address the double… $385,969
Regents Of The University Of Michigan Dr. Flood will lead data collection, analysis, and interpretation of implementation outcomes in Guatemala. Tasks and deliverables include: • Designing… $86,856

Quick answers

Who received award R01HD114708?

R01HD114708 was awarded to Brigham & Womens Hospital Inc. by National Institute of Child Health and Human Development (National Institutes of Health) on December 25, 2024.

How much is award R01HD114708 worth?

$1,757,821 has been obligated on R01HD114708.

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