This federal Project Grant award of $125,814 was provided by the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865). The award supports research by the University of California, San Francisco (UCSF) to quantify germ cell lineage dynamics and characterize germ cell selection during mammalian oogenesis. The research aims to determine the functional importance of early germ cell heterogeneity in...
This Project Grant award from the National Institute of Child Health and Human Development (CFDA 93.865 - Child Health and Human Development Extramural Research) provides $154,000 to The University of Kentucky Research Foundation to investigate the role of long non-coding RNAs (lncRNAs) in the ovulatory process. The research aims to identify the top 5 most highly LH/HCG-regulated lncRNAs and characterize their function in the ovary, particularly the role of the lncRNA GM12648 in regulating genes...
This federal Project Grant award, provided by the National Institute of Child Health and Human Development (NICHD) under CFDA program 93.865 Child Health and Human Development Extramural Research, will fund a multi-disciplinary research effort to uncover novel insights into endocervical mucus secretion. The primary goal is to understand how female sex hormones regulate the biophysical properties of endocervical mucus in order to inform the development of novel, non-hormonal therapeutics for...
This Project Grant award of $724,714 from the National Institute of Child Health and Human Development (NICHD) under CFDA 93.865 Child Health and Human Development Extramural Research supports research to evaluate the effects of exogenous anti-müllerian hormone (AMH) on ovarian function and fertility in non-human primates. The primary awardee, The General Hospital Corporation (doing business as Massachusetts General Hospital), will conduct studies to test hypotheses that supraphysiological AMH...
This federal Project Grant award from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) will provide $232,308 to Magee-Womens Research Institute and Foundation to elucidate the role of the hyaluronan matrices on the establishment and maintenance of the ovarian reserve and reproductive longevity. The research aims to test the hypothesis that the stromal microenvironment of the fetal ovary,...
This Project Grant award from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), is funding research to define the role of apoptosis (programmed cell death) in oogenesis (egg cell production) and oocyte health as a mechanism to control oocyte quality before ovulation. The $221,448 award to the University of North Carolina at Chapel Hill will support experiments using the C. elegans model...
This federal Project Grant award from the National Institute of Child Health and Human Development (CFDA 93.865 - Child Health and Human Development Extramural Research) provides $108,512 to the University of Illinois to investigate the role of salt-inducible kinase 3 (SIK3) in regulating fertility through ovarian granulosa cell function. The research aims to elucidate the upstream regulation, downstream targets, and metabolic effects of SIK3 in granulosa cell differentiation. Specifically,...
This $980,400 Project Grant award was provided by the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865). The award will support research at Kent State University to investigate the role of kisspeptin/neurokinin B/dynorphin (KNDY) neurons in an animal model of polycystic ovary syndrome (PCOS), a leading cause of female infertility. The research aims to define how changes in the regulation of KNDY...
The National Institute of Child Health and Human Development (NICHD) awarded a $147,486 Project Grant under the Child Health and Human Development Extramural Research program (CFDA 93.865) to The Trustees of the University of Pennsylvania, doing business as Clinical Practices of the University of Pennsylvania. The grant, which runs from September 1, 2025 to August 31, 2028, will support research investigating the role of the protein KIF2C in regulating the microtubule cytoskeleton during the...
This Project Grant award, valued at $232,500.00, was provided by the National Institute of Child Health and Human Development under the Child Health and Human Development Extramural Research program (CFDA 93.865). The funding supports research to investigate the role of circular RNA (circRNA) in ovarian follicular development and fertility. The project will examine the effect of the KHDRBS1 protein on circRNA biogenesis and its impact on fertility using a granulosa cell-specific KHDRBS1 knockout...