Developmental effects of antenatal exposure to antipsychotics
Active Project Grant Awarded Last action
- Award ID
- R01HD111117
- Recipient
-
Icahn School Of Medicine At Mount Sinai UEI C8H9CNG1VBD9
- Awarding agency
-
National Institute of Child Health and Human Development
National Institutes of Health, Department of Health and Human Services
- Obligated
- $4,233,820
Award facts
- Assistance listing
- 93.865 Child Health and Human Development Extramural Research
- Completion date 69% complete
- Place of performance
- New York, NY 10029, USA
Award details come from USAspending.gov.
Description
- Abstract
- Antipsychotics are a class of commonly used medications that are used for multiple indications within psychiatry, including psychosis, mood stabilization, and augmentation for depression. The use of antipsychotics among pregnant and lactating women has increased in frequency in recent years. However, their efficacy has not been directly tested in this population, and many unanswered questions remain about the potential effects of antipsychotics on the development of the fetus, neonate, and infant. We propose to conduct a prospective observational study of maternal psychiatric course and infant development among women with severe mental illness, comparing women treated with antipsychotics to women treated with other medications or without medication. The primary study outcomes will be psychiatric relapse in the mother, EEG abnormalities in the infant at 6 months, and behavioral and psychosocial outcomes at 18 months. We hope to determine whether antipsychotics are effective for pregnant women with severe mental illness and whether they have any measurable effects on infant development. This information will help women with severe mental illness make informed decisions about their care in pregnancy.
Transactions
| Action | Obligated | Date |
|---|---|---|
| Amendment | $180,187 | |
| Amendment | $459,295 | |
| Amendment | $459,295 | |
| Amendment | $642,029 | |
| Amendment | $611,394 | |
| Amendment | $611,394 | |
| Amendment | $635,113 | |
| Original award | $635,113 |
Subawards
| Subrecipient | Amount | Awarded |
|---|---|---|
| Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC) | $180,187 | |
| Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC) | $511,117 |
Quick answers
Who received award R01HD111117?
R01HD111117 was awarded to Icahn School Of Medicine At Mount Sinai by National Institute of Child Health and Human Development (National Institutes of Health) on June 1, 2023.
How much is award R01HD111117 worth?
$4,233,820 has been obligated on R01HD111117.
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